Table 4.

Endocrine profile of the pituitary-gonadal axis in female patients before and after busulfan conditioning and beti-cel infusion

Before busulfan conditioning and beti-cel infusionAfter busulfan conditioning and beti-cel infusion
Patient 4Patient 5Patient 7Patient 4Patient 5Patient 7
LH, U/L (normal, 0.60-13.72) 5.1 4.47 10.99 15.6 39.6 6.18 
FSH, U/L (normal, 0.97-11.60) 3.3 6.47 13.87 n.a. 95.8 42.58 
Estradiol, pg/mL (normal, 40-250) n.a. n.a. 12.6  18.6 <11.8 <11.8  
AMH, ng/mL (normal, 1.2-9.5) 3.31 n.a. 0.03 <0.02 0.01 0.01 
Before busulfan conditioning and beti-cel infusionAfter busulfan conditioning and beti-cel infusion
Patient 4Patient 5Patient 7Patient 4Patient 5Patient 7
LH, U/L (normal, 0.60-13.72) 5.1 4.47 10.99 15.6 39.6 6.18 
FSH, U/L (normal, 0.97-11.60) 3.3 6.47 13.87 n.a. 95.8 42.58 
Estradiol, pg/mL (normal, 40-250) n.a. n.a. 12.6  18.6 <11.8 <11.8  
AMH, ng/mL (normal, 1.2-9.5) 3.31 n.a. 0.03 <0.02 0.01 0.01 

AMH, anti–Müllerian hormone; FSH, follicle-stimulating hormone; LH, luteinizing hormone; n.a., not available.

Receiving hormonal contraception.

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