TRAEs of any grade (in more than 10% of patients) or grade 3 or higher (in more than 2% of patients)
| Preferred term . | Total, (N = 57) . | |
|---|---|---|
| Any grade . | Grade ≥3 . | |
| Any TRAEs, n (%) | 56 (98) | 19 (33) |
| Nausea | 37 (65) | 0 |
| Fatigue | 28 (49) | 2 (4) |
| Peripheral sensory neuropathy | 25 (44) | 2 (4) |
| Alopecia | 20 (35) | 0 |
| Diarrhea | 18 (32) | 1 (2) |
| Constipation | 15 (26) | 0 |
| Alanine aminotransferase increased | 9 (16) | 6 (11) |
| Headache | 9 (16) | 0 |
| Vomiting | 9 (16) | 0 |
| Stomatitis | 8 (14) | 0 |
| Aspartate aminotransferase increased | 7 (12) | 2 (4) |
| Decreased appetite | 7 (12) | 0 |
| Rash maculopapular | 7 (12) | 1 (2) |
| Dyspepsia | 6 (11) | 0 |
| Myalgia | 6 (11) | 0 |
| Neutropenia | 6 (11) | 5 (9) |
| Pyrexia | 5 (9) | 2 (4) |
| Pneumonitis | 3 (5) | 2 (4) |
| Colitis | 2 (4) | 2 (4) |
| Preferred term . | Total, (N = 57) . | |
|---|---|---|
| Any grade . | Grade ≥3 . | |
| Any TRAEs, n (%) | 56 (98) | 19 (33) |
| Nausea | 37 (65) | 0 |
| Fatigue | 28 (49) | 2 (4) |
| Peripheral sensory neuropathy | 25 (44) | 2 (4) |
| Alopecia | 20 (35) | 0 |
| Diarrhea | 18 (32) | 1 (2) |
| Constipation | 15 (26) | 0 |
| Alanine aminotransferase increased | 9 (16) | 6 (11) |
| Headache | 9 (16) | 0 |
| Vomiting | 9 (16) | 0 |
| Stomatitis | 8 (14) | 0 |
| Aspartate aminotransferase increased | 7 (12) | 2 (4) |
| Decreased appetite | 7 (12) | 0 |
| Rash maculopapular | 7 (12) | 1 (2) |
| Dyspepsia | 6 (11) | 0 |
| Myalgia | 6 (11) | 0 |
| Neutropenia | 6 (11) | 5 (9) |
| Pyrexia | 5 (9) | 2 (4) |
| Pneumonitis | 3 (5) | 2 (4) |
| Colitis | 2 (4) | 2 (4) |