Clinicopathologic features of TP53-mutated AML and AML-MR with wild-type TP53
| Characteristic . | AML-TP53 by ICC (n = 96) . | AML-MR (n = 45) . | P value . |
|---|---|---|---|
| Age at dx (y), median (range) | 68.8 (28-88) | 68.9 (41-91) | NS |
| CK, n (%) | 92 (99) | 12 (27) | <.0001 |
| MK, n (%) | 89 (97) | 12 (27) | <.0001 |
| No. of unique genes mutated, median (range) | 1 (1-4) | 3 (0-6) | <.0001 |
| Intensive induction, n (%) | 35 (36) | 24 (53) | NS |
| SCT, n (%) | 9 (10) | 10 (23) | NS |
| Characteristic . | AML-TP53 by ICC (n = 96) . | AML-MR (n = 45) . | P value . |
|---|---|---|---|
| Age at dx (y), median (range) | 68.8 (28-88) | 68.9 (41-91) | NS |
| CK, n (%) | 92 (99) | 12 (27) | <.0001 |
| MK, n (%) | 89 (97) | 12 (27) | <.0001 |
| No. of unique genes mutated, median (range) | 1 (1-4) | 3 (0-6) | <.0001 |
| Intensive induction, n (%) | 35 (36) | 24 (53) | NS |
| SCT, n (%) | 9 (10) | 10 (23) | NS |
Abbreviations are explained in Tables 1 and 2.