Base case results: costs and outcomes in a medium baseline ABR scenario
| Parameter . | Voncento LTP . | Voncento ODT . |
|---|---|---|
| Costs | ||
| Total costs | £1 718 847 | £2 550 053 |
| Drug costs | £1 709 462 | £2 239 033 |
| Prophylaxis | £1 636 822 | £0 |
| Bleed-related | £72 640 | £2 239 033 |
| Other medical costs | ||
| Outpatient visit | £1010 | £28 440 |
| Hospitalization | £8375 | £282 297 |
| Joint surgeries | £0 | £283 |
| Outcomes | ||
| QALYs | 11.30 | 5.16 |
| Life years | 32.63 | 32.63 |
| Joint bleeds | 7.32 | 192.00 |
| Joint surgeries | 0.00 | 0.62 |
| Minor bleeds | 23.01 | 538.69 |
| Major bleeds | 9.86 | 332.38 |
| Incremental cost per QALY gained | ||
| Voncento LTP vs Voncento ODT | –£135 311/QALY gained (Voncento LTP dominates) |
| Parameter . | Voncento LTP . | Voncento ODT . |
|---|---|---|
| Costs | ||
| Total costs | £1 718 847 | £2 550 053 |
| Drug costs | £1 709 462 | £2 239 033 |
| Prophylaxis | £1 636 822 | £0 |
| Bleed-related | £72 640 | £2 239 033 |
| Other medical costs | ||
| Outpatient visit | £1010 | £28 440 |
| Hospitalization | £8375 | £282 297 |
| Joint surgeries | £0 | £283 |
| Outcomes | ||
| QALYs | 11.30 | 5.16 |
| Life years | 32.63 | 32.63 |
| Joint bleeds | 7.32 | 192.00 |
| Joint surgeries | 0.00 | 0.62 |
| Minor bleeds | 23.01 | 538.69 |
| Major bleeds | 9.86 | 332.38 |
| Incremental cost per QALY gained | ||
| Voncento LTP vs Voncento ODT | –£135 311/QALY gained (Voncento LTP dominates) |