Table 3.

Outcomes at index therapy by index treatment subset by 1L IC

Treatment groupBRR-CHOP
n%2-year EFS (95% CI)5-year OS (95% CI)n%2-year EFS (95% CI)5-year OS (95% CI)
All treatments 92 100 20% (13-31) 66% (56-79) 128 100 26% (20-35) 73% (66-82) 
Anti-CD20 monotherapy 31% (10-96) 54% (26-100) 10 40% (19-85) 89% (71-100) 
Bendamustine ± CD20 0% (NA to NA) 100% (100-100) 30 23 32% (19-54) 72% (56-93) 
CHOP ± CD20 44 48 15% (7-31) 65% (51-83) 50% (13-100) 100% (100-100) 
Intensive salvage therapy 33% (7-100) 100% (100-100) 48 38 19% (10-34) 61% (49-77) 
Lenalidomide based 10 11 50% (27-93) 83% (58-100) 22% (7-75) 83% (58-100) 
Nonsystemic 50% (13-100) 100% (100-100) 50% (19-100) 100% (100-100) 
Other chemotherapy 0% (NA to NA) 36% (12-100) 25% (8-83) 100% (100-100) 
Radioimmunotherapy 33% (7-100) 67% (30-100) 33% (13-84) 50% (25-100) 
Targeted therapy 11 12 9% (1-59) 70% (42-100) 12% (2-78) 100% (100-100) 
Treatment groupBRR-CHOP
n%2-year EFS (95% CI)5-year OS (95% CI)n%2-year EFS (95% CI)5-year OS (95% CI)
All treatments 92 100 20% (13-31) 66% (56-79) 128 100 26% (20-35) 73% (66-82) 
Anti-CD20 monotherapy 31% (10-96) 54% (26-100) 10 40% (19-85) 89% (71-100) 
Bendamustine ± CD20 0% (NA to NA) 100% (100-100) 30 23 32% (19-54) 72% (56-93) 
CHOP ± CD20 44 48 15% (7-31) 65% (51-83) 50% (13-100) 100% (100-100) 
Intensive salvage therapy 33% (7-100) 100% (100-100) 48 38 19% (10-34) 61% (49-77) 
Lenalidomide based 10 11 50% (27-93) 83% (58-100) 22% (7-75) 83% (58-100) 
Nonsystemic 50% (13-100) 100% (100-100) 50% (19-100) 100% (100-100) 
Other chemotherapy 0% (NA to NA) 36% (12-100) 25% (8-83) 100% (100-100) 
Radioimmunotherapy 33% (7-100) 67% (30-100) 33% (13-84) 50% (25-100) 
Targeted therapy 11 12 9% (1-59) 70% (42-100) 12% (2-78) 100% (100-100) 

1L, first line; NA, not available.

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