Table 1. Distribution of genomic lesions... | American Society of Hematology

Table 1.

Distribution of genomic lesions

B-ALL AR	n = 25	T-ALL AR	n = 10
CRLF2r∗	2	SET:NUP214 (ETP†)	2
DUX4r	7	NUP214::ABL1	1
Hyperdiploid with chr9p del	1	NUP98r	2
Hypodiploid	1	KMT2Ar	1
KMT2Ar	7	PICALM::MLLT10	1
MEF2Dr	2	ETP-ALL	2
NUP214::ABL1∗	1	CDKN2A/B del	1
PAX5alt	1
PAX5::JAK2∗	1
UBTF::ATXN7L3	2
B-ALL SR	n = 15	T-ALL SR	n = 7
ETV6::RUNX1	1	Hyperdiploid	2
Hyperdiploid	3	TAL1r	1
PAX5 p.P80R	3	Not classified (NOS)‡	4
ZNF384r	4
NOS‡	4
TOTAL	N = 40		N = 17

B-ALL AR	n = 25	T-ALL AR	n = 10
CRLF2r∗	2	SET:NUP214 (ETP†)	2
DUX4r	7	NUP214::ABL1	1
Hyperdiploid with chr9p del	1	NUP98r	2
Hypodiploid	1	KMT2Ar	1
KMT2Ar	7	PICALM::MLLT10	1
MEF2Dr	2	ETP-ALL	2
NUP214::ABL1∗	1	CDKN2A/B del	1
PAX5alt	1
PAX5::JAK2∗	1
UBTF::ATXN7L3	2
B-ALL SR	n = 15	T-ALL SR	n = 7
ETV6::RUNX1	1	Hyperdiploid	2
Hyperdiploid	3	TAL1r	1
PAX5 p.P80R	3	Not classified (NOS)‡	4
ZNF384r	4
NOS‡	4
TOTAL	N = 40		N = 17

See supplemental Table 1 for individual patient listings and detailed genomic alterations.

ETP, Early T-cell Precursor ALL; Ph-like, Philadelphia-like; NOS, not-otherwise-specified.

Ph-like genomic features.

1 patient has ETP-ALL immunophenotype.

NOS genomic classification.