Calaspargase pegol desensitization procedure for a dose of 2500 units/m2 (assuming body surface area of 1 m2)
| Bag . | Concentration (units/mL) . | Rate (mL/h) . | Time (h) . | Volume infused (mL) . | Dose infused (units) . | Cumulative dose (units) . |
|---|---|---|---|---|---|---|
| 1 (5 units in 100 mL) | 0.05 | 10 | 0.25 | 2.5 | 0.125 | 0.125 |
| 20 | 0.25 | 5 | 0.25 | 0.375 | ||
| 40 | 0.25 | 10 | 0.5 | 0.875 | ||
| 80 | 0.25 | 20 | 1 | 1.875 | ||
| 2 (50 units in 100 mL) | 0.5 | 20 | 0.25 | 5 | 2.5 | 4.375 |
| 40 | 0.25 | 10 | 5 | 9.375 | ||
| 80 | 0.25 | 20 | 10 | 19.375 | ||
| 160 | 0.25 | 40 | 20 | 39.375 | ||
| 3 (2461 units in 246 mL) | 10 | 15 | 0.25 | 3.75 | 37.5 | 76.875 |
| 30 | 0.25 | 7.5 | 75 | 151.875 | ||
| 60 | 0.25 | 15 | 150 | 301.875 | ||
| 120 | 1.83 | 220 | 2198 | 2500 |
| Bag . | Concentration (units/mL) . | Rate (mL/h) . | Time (h) . | Volume infused (mL) . | Dose infused (units) . | Cumulative dose (units) . |
|---|---|---|---|---|---|---|
| 1 (5 units in 100 mL) | 0.05 | 10 | 0.25 | 2.5 | 0.125 | 0.125 |
| 20 | 0.25 | 5 | 0.25 | 0.375 | ||
| 40 | 0.25 | 10 | 0.5 | 0.875 | ||
| 80 | 0.25 | 20 | 1 | 1.875 | ||
| 2 (50 units in 100 mL) | 0.5 | 20 | 0.25 | 5 | 2.5 | 4.375 |
| 40 | 0.25 | 10 | 5 | 9.375 | ||
| 80 | 0.25 | 20 | 10 | 19.375 | ||
| 160 | 0.25 | 40 | 20 | 39.375 | ||
| 3 (2461 units in 246 mL) | 10 | 15 | 0.25 | 3.75 | 37.5 | 76.875 |
| 30 | 0.25 | 7.5 | 75 | 151.875 | ||
| 60 | 0.25 | 15 | 150 | 301.875 | ||
| 120 | 1.83 | 220 | 2198 | 2500 |