Reasons for PFS failure
| . | VAFmut < 50% and not complex/5q/7q . | VAFmut < 50% and complex/5q/7q . | VAFmut ≥ 50% . |
|---|---|---|---|
| Graft rejection or failure | 1 (6.25) | ||
| Infection | 6 (37.5) | 13 (13.1) | 9 (20.9) |
| ARDS | 3 (3.1) | 1 (2.33) | |
| Acute GVHD | 1 (6.25) | 4 (4.1) | 1 (2.33) |
| Chronic GVHD | 2 (2.1) | ||
| Recurrence/persistence of disease | 7 (43.75) | 70 (72.2) | 29 (67.4) |
| Cardiac failure | 1 (2.33) | ||
| VOD | 1 (2.33) | ||
| DAH | 1 (1.1) | 1 (2.33) | |
| Other/unknown | 1 (6.25) | 4 (4.1) | |
| Total | 16 (100) | 97 (100) | 43 (100) |
| . | VAFmut < 50% and not complex/5q/7q . | VAFmut < 50% and complex/5q/7q . | VAFmut ≥ 50% . |
|---|---|---|---|
| Graft rejection or failure | 1 (6.25) | ||
| Infection | 6 (37.5) | 13 (13.1) | 9 (20.9) |
| ARDS | 3 (3.1) | 1 (2.33) | |
| Acute GVHD | 1 (6.25) | 4 (4.1) | 1 (2.33) |
| Chronic GVHD | 2 (2.1) | ||
| Recurrence/persistence of disease | 7 (43.75) | 70 (72.2) | 29 (67.4) |
| Cardiac failure | 1 (2.33) | ||
| VOD | 1 (2.33) | ||
| DAH | 1 (1.1) | 1 (2.33) | |
| Other/unknown | 1 (6.25) | 4 (4.1) | |
| Total | 16 (100) | 97 (100) | 43 (100) |
ARDS, acute respiratory distress syndrome; DAH, diffuse alveolar hemorrhage; VOD/SOS, veno-occlusive disease/sinusoidal obstruction syndrome.