Diagnostic SaO2/FiO2 and clinical outcomes by hospitalization characteristics
| Medical history . | Median SaO2/FiO2 at diagnosis (IQR)† . | ICU transfer (%), n = 52 . | Inpatient death (%), n = 4 . | ||
|---|---|---|---|---|---|
| All admissions N = 227 . | No home O2, n = 184 . | Home O2, n = 43 . | |||
| BMI (kg/m2)‡ | |||||
| Underweight (<18.5) | 334 (273-388) | 388 (334-452) | 288 (246-321) | 12 (33) | 0 (0) |
| Normal (18.5-24.9) | 376 (313-452) | 376 (324-452) | 328 (270-338) | 23 (16) | 2 (1) |
| Overweight (25-29.9) | 334 (288-452) | 445 (334-457) | 288 (254-297) | 9 (33)∗ | 0 (0) |
| Obese (≥30) | 312 (270-450) | 377 (271-464) | 302 (247-373) | 8 (40) | 2 (10) |
| Smoking history§ | |||||
| Never | 344 (310-452) | 384 (324-452) | 300 (254-331) | 27 (18) | 4 (3) |
| Former | 334 (283-452) | 345 (297-457) | 302 (259-334) | 14 (35) | 0 (0) |
| Current | 341 (291-443) | 414 (331-460) | 273 (262-297) | 10 (26) | 0 (0) |
| Asthma | |||||
| Yes | 331 (288-448) | 366 (310-452) | 288 (246-328) | 24 (26) | 1 (1) |
| No | 360 (316-452) | 396 (334-457) | 300 (270-334) | 27 (20) | 3 (2) |
| COPD | |||||
| Yes | 270 (123-288)∗∗ | 123 (123-123)∗∗∗ | 279 (270-288) | 2 (67) | 0 (0) |
| No | 345 (303-452) | 382 (324-457) | 297 (259-328) | 49 (22) | 4 (2) |
| Home oxygen | |||||
| Yes | 297 (259-328)∗∗∗ | - | - | 17 (40) | 0 (0) |
| No | 378 (324-455) | 35 (19) | 4 (2) | ||
| Clinical characteristic | |||||
| Diagnostic chest imaging† | |||||
| 1 lobe | 396 (321-457) | 448 (338-462) | 300 (262-331) | 19 (17) | 3 (3) |
| 2 lobes | 338 (288-443)∗ | 338 (310-443)∗∗ | 286 (259-334) | 21 (23) | 0 (0) |
| ≥3 lobes | 295 (262-345)∗∗∗ | 310 (268-395)∗∗ | 269 (209-300) | 12 (55)∗∗ | 1 (5) |
| Red cell exchange | |||||
| Yes | 282 (246-345)∗∗∗ | 293 (255-370)∗∗∗ | 254 (209-291)∗∗ | 35 (78)∗∗∗ | 2 (4) |
| No | 376 (324-452) | 414 (334-457) | 303 (276-334) | 17 (9) | 2 (1) |
| Medical history . | Median SaO2/FiO2 at diagnosis (IQR)† . | ICU transfer (%), n = 52 . | Inpatient death (%), n = 4 . | ||
|---|---|---|---|---|---|
| All admissions N = 227 . | No home O2, n = 184 . | Home O2, n = 43 . | |||
| BMI (kg/m2)‡ | |||||
| Underweight (<18.5) | 334 (273-388) | 388 (334-452) | 288 (246-321) | 12 (33) | 0 (0) |
| Normal (18.5-24.9) | 376 (313-452) | 376 (324-452) | 328 (270-338) | 23 (16) | 2 (1) |
| Overweight (25-29.9) | 334 (288-452) | 445 (334-457) | 288 (254-297) | 9 (33)∗ | 0 (0) |
| Obese (≥30) | 312 (270-450) | 377 (271-464) | 302 (247-373) | 8 (40) | 2 (10) |
| Smoking history§ | |||||
| Never | 344 (310-452) | 384 (324-452) | 300 (254-331) | 27 (18) | 4 (3) |
| Former | 334 (283-452) | 345 (297-457) | 302 (259-334) | 14 (35) | 0 (0) |
| Current | 341 (291-443) | 414 (331-460) | 273 (262-297) | 10 (26) | 0 (0) |
| Asthma | |||||
| Yes | 331 (288-448) | 366 (310-452) | 288 (246-328) | 24 (26) | 1 (1) |
| No | 360 (316-452) | 396 (334-457) | 300 (270-334) | 27 (20) | 3 (2) |
| COPD | |||||
| Yes | 270 (123-288)∗∗ | 123 (123-123)∗∗∗ | 279 (270-288) | 2 (67) | 0 (0) |
| No | 345 (303-452) | 382 (324-457) | 297 (259-328) | 49 (22) | 4 (2) |
| Home oxygen | |||||
| Yes | 297 (259-328)∗∗∗ | - | - | 17 (40) | 0 (0) |
| No | 378 (324-455) | 35 (19) | 4 (2) | ||
| Clinical characteristic | |||||
| Diagnostic chest imaging† | |||||
| 1 lobe | 396 (321-457) | 448 (338-462) | 300 (262-331) | 19 (17) | 3 (3) |
| 2 lobes | 338 (288-443)∗ | 338 (310-443)∗∗ | 286 (259-334) | 21 (23) | 0 (0) |
| ≥3 lobes | 295 (262-345)∗∗∗ | 310 (268-395)∗∗ | 269 (209-300) | 12 (55)∗∗ | 1 (5) |
| Red cell exchange | |||||
| Yes | 282 (246-345)∗∗∗ | 293 (255-370)∗∗∗ | 254 (209-291)∗∗ | 35 (78)∗∗∗ | 2 (4) |
| No | 376 (324-452) | 414 (334-457) | 303 (276-334) | 17 (9) | 2 (1) |
∗P < .05; ∗∗P < .01; ∗∗∗P < .001.
IQR, interquartile range.
Statistical associations assessed with multilevel linear regression models of logarithmic transformation of diagnostic SaO2/FiO2 ratio.
BMI dichotomized into underweight vs normal BMI as well as overweight/obese vs normal BMI in multilevel linear and logistic regression models for each column. Thus, 2 models were run for each column, and P values where indicated signify a significant difference between underweight and normal BMI or between overweight/obese and normal BMI.
Smoking dichotomized into never vs prior/current in multilevel linear and logistic regression models.