Table 2.

Demographic, clinical, and laboratory data of the sibling controls vs SCA samples at enrollment (month 0)

Controls (N = 110)SCA
Month 0 (N = 264)
P value
Age (y) 7.6 ± 3.0 5.6 ± 1.2 <.001 
Sex (female) 63 (57.3%) 137 (51.9%) .34 
Malnutrition (%) n = 79
3 (3.8%) 
n = 262
24 (9.2%) 
.16 
Hb (g/dL) n = 105
12.5 ± 1.1 
7.8 ± 1.2 <.001 
Socioeconomic scale  7.1 ± 2.6 6.6 ± 2.3 .12 
Caregiver education     
Lower 41 (37.3%) 102 (38.6%) .81 
Higher 69 (62.7%) 162 (61.4%)  
Controls (N = 110)SCA
Month 0 (N = 264)
P value
Age (y) 7.6 ± 3.0 5.6 ± 1.2 <.001 
Sex (female) 63 (57.3%) 137 (51.9%) .34 
Malnutrition (%) n = 79
3 (3.8%) 
n = 262
24 (9.2%) 
.16 
Hb (g/dL) n = 105
12.5 ± 1.1 
7.8 ± 1.2 <.001 
Socioeconomic scale  7.1 ± 2.6 6.6 ± 2.3 .12 
Caregiver education     
Lower 41 (37.3%) 102 (38.6%) .81 
Higher 69 (62.7%) 162 (61.4%)  

Bold values indicate significance at P < .05.

Defined as weight-for-age z-score <−2, by sex, per WHO global standards.13 

Socioeconomic status, per a locally validated scale from 6 to 18.24 

Defined as lower (none or primary) or higher (secondary, tertiary, or higher).

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