Table 2.

Characteristics of included studies used to calculate pooled prevalence of SCT among patients with CKD/ESRD

Author, yearCountryTotal sampleNo of SCTSites of enrollmentSCT diagnosisCKD/ESRD diagnosisCohort characteristics
Derebail et al,36 2014 United States 5319 542 Patients undergoing hemodialysis at 117 in-center hemodialysis clinics from Eastern United States Hb electrophoresis Patients in dialysis treatment Mean age (SD): 60.1 (14.1) years
Male: 50.6%
Hypertense: NI
Diabetic: 51.7% 
Derebail et al,35 2010 United States 187 28 4 dialysis units in North Carolina HPLC Patients in dialysis treatment Mean age (SD): 59.3 (14.7) years
Male: 52.4%
Hypertense: 36.4%
Diabetic: 40.1% 
Hicks et al,27 2011 United States 2081 164 Patients with ESRD from North Carolina, South Carolina, Georgia, Virginia, or Tennessee Direct genotyping Patients in dialysis treatment Mean age (SD): 57.8 (12.5) years
Male: 48.2%
Hypertense: NI
Diabetic: 47.9% 
Mukendi et al,26 2015 Africa 188 39 Patients from secondary and tertiary care hospitals in the Democratic Republic of the Congo Electrophoresis eGFR <60 mL/min per 1.73 m2 Mean age (SD): 55.5 (16) years
Male: 48.8%
Hypertense: 39%
Diabetic: 44% 
Sood et al,34 2019 United States 652 65 11 clinical centers located in Cleveland, Ohio; Nashville, Tennessee; Dallas, Texas; Baltimore, Maryland; Washington, DC; Atlanta, Georgia; and Los Angeles, California Genotyping Hypertension-attributed CKD (mGFR 20-65 mL/min per 1.73 m2Mean age (SD): 54 (10.8) years
Male: 59.8%
Hypertense: 100%
Diabetic: NI 
Author, yearCountryTotal sampleNo of SCTSites of enrollmentSCT diagnosisCKD/ESRD diagnosisCohort characteristics
Derebail et al,36 2014 United States 5319 542 Patients undergoing hemodialysis at 117 in-center hemodialysis clinics from Eastern United States Hb electrophoresis Patients in dialysis treatment Mean age (SD): 60.1 (14.1) years
Male: 50.6%
Hypertense: NI
Diabetic: 51.7% 
Derebail et al,35 2010 United States 187 28 4 dialysis units in North Carolina HPLC Patients in dialysis treatment Mean age (SD): 59.3 (14.7) years
Male: 52.4%
Hypertense: 36.4%
Diabetic: 40.1% 
Hicks et al,27 2011 United States 2081 164 Patients with ESRD from North Carolina, South Carolina, Georgia, Virginia, or Tennessee Direct genotyping Patients in dialysis treatment Mean age (SD): 57.8 (12.5) years
Male: 48.2%
Hypertense: NI
Diabetic: 47.9% 
Mukendi et al,26 2015 Africa 188 39 Patients from secondary and tertiary care hospitals in the Democratic Republic of the Congo Electrophoresis eGFR <60 mL/min per 1.73 m2 Mean age (SD): 55.5 (16) years
Male: 48.8%
Hypertense: 39%
Diabetic: 44% 
Sood et al,34 2019 United States 652 65 11 clinical centers located in Cleveland, Ohio; Nashville, Tennessee; Dallas, Texas; Baltimore, Maryland; Washington, DC; Atlanta, Georgia; and Los Angeles, California Genotyping Hypertension-attributed CKD (mGFR 20-65 mL/min per 1.73 m2Mean age (SD): 54 (10.8) years
Male: 59.8%
Hypertense: 100%
Diabetic: NI 

mGFR, measured glomerular filtration rate; NI, not included; SD, standard deviation.

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