Table 2.

Response rates

Entire study cohort (N = 16)MonotherapyMonotherapy + induction 
Day 35Day 77Day 77
n%n%n%
CR 18.8 18.8 37.5 
PR 13.5 6.3 
No response  11 67.7 13 81.2 56.2 
ORR (CR + PR) 31.3 18.8 43.8 
Entire study cohort (N = 16)MonotherapyMonotherapy + induction 
Day 35Day 77Day 77
n%n%n%
CR 18.8 18.8 37.5 
PR 13.5 6.3 
No response  11 67.7 13 81.2 56.2 
ORR (CR + PR) 31.3 18.8 43.8 

Induction therapies (n = 6) included fludarabine, cytarabine, and granulocyte colony-stimulating factor (n = 3); decitabine and venetoclax (n = 2); mitoxantrone, etoposide, and cytarabine (n = 1).

Includes progression, nonresponse/SD, not assessed, or received other leukemia-directed therapy.

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