Table 2. Adjusted Cox regression... | American Society of Hematology

Table 2.

Adjusted Cox regression analyses to identify predictors of OS from first-line therapy

	Adjusted∗
	HR (95% CI)	P value
Age
60-69†	1.51 (1.34-1.69)	<.0001
70-79†	2.30 (2.06-2.56)	<.0001
≥80†	3.64 (3.25-4.09)	<.0001
Sex
Male	1.26 (1.17-1.35)	<.0001
Days from diagnosis to treatment‡
0-28	1.18 (1.07-1.30)	.0009
29-56	0.97 (0.88-1.05)	.42
LDH
200-399	1.14 (1.02-1.26)	.017
≥400	1.59 (1.48-1.7)	<.0001
Unknown	1.06 (1.05-1.06)	<.0001

	Adjusted∗
	HR (95% CI)	P value
Age
60-69†	1.51 (1.34-1.69)	<.0001
70-79†	2.30 (2.06-2.56)	<.0001
≥80†	3.64 (3.25-4.09)	<.0001
Sex
Male	1.26 (1.17-1.35)	<.0001
Days from diagnosis to treatment‡
0-28	1.18 (1.07-1.30)	.0009
29-56	0.97 (0.88-1.05)	.42
LDH
200-399	1.14 (1.02-1.26)	.017
≥400	1.59 (1.48-1.7)	<.0001
Unknown	1.06 (1.05-1.06)	<.0001

Adjusted for frailty, comorbidity burden as measured by aggregated diagnosis groups, income quintile, and rurality.

Reference group, age 18 to 59 years.

Reference group, >56 days.