Survival estimates and hazard ratios of combination duv/romi in multicenter R/R cohort
| . | HR [95% CI] (P value) . | ||
|---|---|---|---|
| nTFH vs non-nTFH (ref) . | nTFH vs PTCL-NOS vs all other (ref) . | CRR/PRR (ref) vs progression . | |
| OS∗ | |||
| Standard censoring | 0.72 [0.26-2.02] (.5) | nTFH: 0.74 [0.18-3.0] (.7); PTCL-NOS: 1.0 [0.26-4.2] (.96) | 17.9 [3.9-82] (.0002) |
| Allo-HSCT–censored | 0.66 [0.23-1.87] (.4) | nTFH: 0.66 [0.16-2.7] (.6); PTCL-NOS: 0.99 [0.25-4.0] (.99) | 13.0 [2.9-58] (.0008) |
| PFS∗ | |||
| Standard censoring | 0.44 [0.18-1.09] (.07) | nTFH: 0.82 [0.21-3.2] (.8) PTCL-NOS: 2.50 [0.68-9.2] (.2) | — |
| Allo-HSCT–censored | 0.31 [0.11-0.87] (.03) | nTFH: 0.45 [0.12-1.7] (.2) PTCL-NOS: 1.84 [0.57-6.0] (.3) | — |
| EFS∗ | |||
| Standard censoring | 0.45 [0.19-1.07] (.07) | nTFH: 0.93 [0.25-3.5] (.9) PTCL-NOS: 2.9 [0.80-11] (.1) | |
| Allo-HSCT–censored | 0.31 [0.11-0.87] (.03) | nTFH: 0.45 [0.12-1.7] (.2) PTCL-NOS: 1.84 [0.57-6.0] (.3) | |
| Treatment response and duration | |||
| ORR | P† = .02 | ||
| TTNT | P‡ = .2 | ||
| Time of follow-up | P‡ = .9 | ||
| TTR | P§ = .3 | ||
| DoR | P‡ = .8 | ||
| . | HR [95% CI] (P value) . | ||
|---|---|---|---|
| nTFH vs non-nTFH (ref) . | nTFH vs PTCL-NOS vs all other (ref) . | CRR/PRR (ref) vs progression . | |
| OS∗ | |||
| Standard censoring | 0.72 [0.26-2.02] (.5) | nTFH: 0.74 [0.18-3.0] (.7); PTCL-NOS: 1.0 [0.26-4.2] (.96) | 17.9 [3.9-82] (.0002) |
| Allo-HSCT–censored | 0.66 [0.23-1.87] (.4) | nTFH: 0.66 [0.16-2.7] (.6); PTCL-NOS: 0.99 [0.25-4.0] (.99) | 13.0 [2.9-58] (.0008) |
| PFS∗ | |||
| Standard censoring | 0.44 [0.18-1.09] (.07) | nTFH: 0.82 [0.21-3.2] (.8) PTCL-NOS: 2.50 [0.68-9.2] (.2) | — |
| Allo-HSCT–censored | 0.31 [0.11-0.87] (.03) | nTFH: 0.45 [0.12-1.7] (.2) PTCL-NOS: 1.84 [0.57-6.0] (.3) | — |
| EFS∗ | |||
| Standard censoring | 0.45 [0.19-1.07] (.07) | nTFH: 0.93 [0.25-3.5] (.9) PTCL-NOS: 2.9 [0.80-11] (.1) | |
| Allo-HSCT–censored | 0.31 [0.11-0.87] (.03) | nTFH: 0.45 [0.12-1.7] (.2) PTCL-NOS: 1.84 [0.57-6.0] (.3) | |
| Treatment response and duration | |||
| ORR | P† = .02 | ||
| TTNT | P‡ = .2 | ||
| Time of follow-up | P‡ = .9 | ||
| TTR | P§ = .3 | ||
| DoR | P‡ = .8 | ||