Baseline characteristics
| Baseline characteristics . | Thr/Thr n = 24 . | Thr/Ala or Ala/Ala n = 98 . | P value . |
|---|---|---|---|
| Age, y | 31.6 ± 6.0 | 31.7 ± 6.1 | .96 |
| Race | <0.001 | ||
| Black, Non-Hispanic | 50 (50.5%) | 23 (95.8%) | |
| White, Non-Hispanic | 32 (32.3%) | 0 | |
| Asian | 5 (3.9%) | 0 | |
| Hispanic, White | 11 (11.1%) | 1 (4.2%) | |
| Other | 1 (1.0%) | 0 | |
| Weight | 207.8 ± 44.3 | 202.2 ± 53.1 | .59 |
| Obesity, BMI of >30 kg/m2 | 18 (75.0) | 66 (67.3) | .63 |
| Hypertension | 9 (37.5) | 29 (29.6) | .61 |
| Diabetes | 2 (8.3) | 11 (11.2) | 1.0 |
| Nulliparous | 2 (8.3) | 36 (36.7) | .01 |
| Previous preeclampsia | 9/22 (40.9) | 27/62 (43.5) | 1.0 |
| Previous preterm birth | 11/22 (50.0) | 10/62 (16.1) | .004 |
| Previous preterm preeclampsia | 6/22 (27.3) | 6/62 (9.7) | .07 |
| PFA-100 (before aspirin) | 137.1 ± 44.3 | 129.1 ± 37.6 | .42 |
| Baseline characteristics . | Thr/Thr n = 24 . | Thr/Ala or Ala/Ala n = 98 . | P value . |
|---|---|---|---|
| Age, y | 31.6 ± 6.0 | 31.7 ± 6.1 | .96 |
| Race | <0.001 | ||
| Black, Non-Hispanic | 50 (50.5%) | 23 (95.8%) | |
| White, Non-Hispanic | 32 (32.3%) | 0 | |
| Asian | 5 (3.9%) | 0 | |
| Hispanic, White | 11 (11.1%) | 1 (4.2%) | |
| Other | 1 (1.0%) | 0 | |
| Weight | 207.8 ± 44.3 | 202.2 ± 53.1 | .59 |
| Obesity, BMI of >30 kg/m2 | 18 (75.0) | 66 (67.3) | .63 |
| Hypertension | 9 (37.5) | 29 (29.6) | .61 |
| Diabetes | 2 (8.3) | 11 (11.2) | 1.0 |
| Nulliparous | 2 (8.3) | 36 (36.7) | .01 |
| Previous preeclampsia | 9/22 (40.9) | 27/62 (43.5) | 1.0 |
| Previous preterm birth | 11/22 (50.0) | 10/62 (16.1) | .004 |
| Previous preterm preeclampsia | 6/22 (27.3) | 6/62 (9.7) | .07 |
| PFA-100 (before aspirin) | 137.1 ± 44.3 | 129.1 ± 37.6 | .42 |
Thr/Ala or Ala/Ala represents PAR4-Thr120 genotype homozygous for Ala or heterozygous for Ala and Thr at position 120; and Thr/Thr, PAR4-120 variant homozygous for Thr. Data are presented as mean ± standard deviation or n (%) as appropriate.
BMI, body mass index.