Table 3.

Gene expression of OR4N5, OR2A7, OR6C68, and OR10K2 in 6 cancers vs normal control

Gene nameBreast carcinomaColorectal carcinomaGlioblastoma
P valuelog2FCP valuelog2FCP valuelog2FC
OR4N5 5.08E−05 −3.3 .000203805 −3 .037922805 −1.5 
OR10K2 1.99E−16 −5 1.61E−21 −5.8 4.81E−06 −2.6 
OR2A7 2.47E−19 −4.7 8.42E−23 −5.5 1.18E−05 −2.2 
OR6C68 1.25E−06 −3.4 9.69E−09 −3.8 .00392438 −1.8 
Gene nameBreast carcinomaColorectal carcinomaGlioblastoma
P valuelog2FCP valuelog2FCP valuelog2FC
OR4N5 5.08E−05 −3.3 .000203805 −3 .037922805 −1.5 
OR10K2 1.99E−16 −5 1.61E−21 −5.8 4.81E−06 −2.6 
OR2A7 2.47E−19 −4.7 8.42E−23 −5.5 1.18E−05 −2.2 
OR6C68 1.25E−06 −3.4 9.69E−09 −3.8 .00392438 −1.8 
Gene nameHepatobiliary carcinomaNSC lung carcinomaPancreatic adenocarcinoma
P valuelog2FCP valuelog2FCP valuelog2FC
OR4N5 .04766668 −1.9 5.79E−05 −2.5 4.44E−05 −3.4 
OR10K2 .00153234 −2.3 7.77E−11 −3.7 1.18E−07 −3.5 
OR2A7 .0001452 −2.7 6.51E−16 −4.1 2.37E−07 −3 
OR6C68 .00590347 −2.3 5.17E−06 −2.6 1.46E−10 −4.4 
Gene nameHepatobiliary carcinomaNSC lung carcinomaPancreatic adenocarcinoma
P valuelog2FCP valuelog2FCP valuelog2FC
OR4N5 .04766668 −1.9 5.79E−05 −2.5 4.44E−05 −3.4 
OR10K2 .00153234 −2.3 7.77E−11 −3.7 1.18E−07 −3.5 
OR2A7 .0001452 −2.7 6.51E−16 −4.1 2.37E−07 −3 
OR6C68 .00590347 −2.3 5.17E−06 −2.6 1.46E−10 −4.4 

Gene expression levels of OR4N5, OR2A7, OR6C68, and OR10K2 in 6 types of cancer compared to normal controls, based on data from the E-GEOD-68086 data set (EMBL-EBI). OR4N5, OR2A7, and OR6C68 are predominantly expressed in blood tissues, whereas OR10K2, induced by CSH71, is included as a control. All data are presented as log2FC with P values <.05.

EMBL-EBI, European Molecular Biology Laboratory – European Bioinformatics Institute; FC, fold change; NSC, non-small cell.

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