Table 2.

eDiary mobile application acute SCD pain incidence rates vs hospitalization acute SCD pain incidence rates during pregnancy (third trimester to 6 weeks after childbirth) and after pregnancy (6 to 9 months after childbirth) in 33 participants assessed during pregnancy and after pregnancy

Data source for capturing acute SCD pain events
PeriodeDiary mobile application Hospitalization P value (comparison between data sources)
Third trimester to 6 weeks after childbirth 0.74 (95% CI, 0.61-0.90) 0.14 (95% CI, 0.08-0.22) <.001 
6 to 9 months after childbirth 0.40 (95% CI, 0.30-0.53) 0.02 (95% CI, 0.00-0.06) <.001 
P value (comparison between periods) <.001 <.001  
Data source for capturing acute SCD pain events
PeriodeDiary mobile application Hospitalization P value (comparison between data sources)
Third trimester to 6 weeks after childbirth 0.74 (95% CI, 0.61-0.90) 0.14 (95% CI, 0.08-0.22) <.001 
6 to 9 months after childbirth 0.40 (95% CI, 0.30-0.53) 0.02 (95% CI, 0.00-0.06) <.001 
P value (comparison between periods) <.001 <.001  

Forty women with SCD were recruited into the study. After enrollment, 17.5% (7/40) of the participants were lost to follow-up and completed no eDiary mobile application entries. A total of 82.5% (33/40) completed the eDiary mobile application during the pregnancy interval (third trimester to 6 weeks after childbirth) and the after-pregnancy interval (beginning at 6 months to end of 9 months after childbirth). Table 2, therefore, includes data for only the 33 participants who completed the eDiary entries.

The clinical outcomes were an eDiary self-report of acute SCD pain and a chief complaint of acute SCD pain requiring hospitalization, which lasted for at least 2 hours and required opioid treatment.

Acute SCD pain events per person-month.

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