VV ECMO baseline characteristics
| . | Total (n = 80) . | Survivors (n = 49) . | Nonsurvivors (n = 31) . | P value . |
|---|---|---|---|---|
| Age, median (25th-75th percentile), y | 26 (22-31) | 25 (22-31) | 27 (22-35) | .29 |
| Sex, n (%) | .52 | |||
| Male | 41 (51.3) | 25 (51) | 16 (51.6) | |
| Female | 37 (46.3) | 22 (44.9) | 15 (48.4) | |
| Unknown | 2 (2.5) | 2 (4.1) | 0 (0) | |
| Weight, median (25th-75th percentile), kg | 74.1 (63.6-91) | 73 (62.8-90.4) | 80 (65.8-93.2) | .36 |
| Height, mean ± SD, cm | 168.1 ± 11.2 | 167.8 ± 10.9 | 168.5 ± 11.8 | .81 |
| BMI, median (25th-75th percentile), kg/m2 | 26.4 (23.1-31) | 26.6 (22.8-30.5) | 28.2 (23.2-32) | .90 |
| Race, n (%) | .25 | |||
| Black | 66 (82.5) | 39 (79.6) | 27 (87.1) | |
| Hispanic | 1 (1.3) | 0 (0) | 1 (3.2) | |
| Middle Eastern/Northern African | 0 (0) | 0 (0) | 0 (0) | |
| Native American | 1 (1.3) | 0 (0) | 1 (3.2) | |
| White | 0 (0) | 0 (0) | 0 (0) | |
| Multiple | 6 (7.5) | 6 (12.2) | 0 (0) | |
| Other | 2 (2.5) | 1 (2) | 1 (3.2) | |
| Unknown | 3 (3.8) | 2 (4.1) | 1 (3.2) | |
| Support type, n (%) | — | |||
| Cardiac | 0 (0) | 0 (0) | 0 (0) | |
| eCPR | 0 (0) | 0 (0) | 0 (0) | |
| Pulmonary | 80 (100) | 49 (100) | 31 (100) | |
| Pre-ECLS arrest, n (%) | 8 (10) | 4 (8.2) | 4 (12.9) | .76 |
| Ventilator status, n (%) | .17 | |||
| Conventional | 64 (80) | 39 (79.6) | 25 (80.6) | |
| No ventilator | 1 (1.3) | 0 (0) | 1 (3.2) | |
| HFO | 3 (3.8) | 3 (6.1) | 0 (0) | |
| Other | 1 (1.3) | 0 (0) | 1 (3.2) | |
| Ventilator settings | ||||
| Respiratory rate (breaths per min), mean ± SD | 25 ± 8 | 24 ± 8 | 26 ± 7 | .33 |
| FiO2, median (25th-75th percentile), % | 100 (100-100) | 100 (100-100) | 100 (91-100) | .19 |
| PIP, median (25th-75th percentile), cm H2O | 36 (32-43) | 37 (31-46) | 35 (34-37) | .18 |
| PEEP, median (25th-75th percentile), cm H2O | 14 (10-17) | 14 (10-18) | 12 (10-14) | .25 |
| Mean airway pressure, median (25th-75th percentile), cm H2O | 23 (19-26) | 24 (20-28) | 20 (19-23) | .02 |
| Required hand-bagging, n (%) | 9 (11.3) | 5 (10.2) | 4 (12.9) | .36 |
| Laboratory values and vital signs | ||||
| pH, median (25th-75th percentile) | 7.28 (7.19-7.36) | 7.30 (7.20-7.37) | 7.25 (7.20-7.34) | .59 |
| pCO2, mean ± SD, mm Hg | 57 ± 19 | 56 ± 20 | 57 ± 18 | .85 |
| pO2, median (25th-75th percentile), mm Hg | 65 (55-79) | 66 (56-76) | 64 (55-82) | .96 |
| Serum bicarbonate, mean ± SD, mmol/L | 26 ± 7 | 26 ± 6 | 26 ±8 | .94 |
| SaO2, median (25th-75th percentile), % | 89 (81-94) | 89 (80-93) | 91 (82-95) | .88 |
| Lactate, median (25th-75th percentile), mmol/L | 2.4 (1.1-3.9) | 2.4 (1.1-3.9) | 2.5 (1.3-3.6) | .87 |
| Systolic blood pressure, mean ± SD, mm Hg | 116 ± 24 | 115 ± 25 | 116 ± 23 | .95 |
| Diastolic blood pressure, mean ± SD, mm Hg | 63 ± 17 | 63 ± 19 | 64 ± 14 | .88 |
| Mean arterial pressure, mean ± SD, mm Hg | 78 ± 19 | 78 ± 21 | 78 ± 18 | .88 |
| Pulse pressure, mean ± SD, mm Hg | 51 ± 18 | 51 ± 18 | 52 ± 18 | .87 |
| . | Total (n = 80) . | Survivors (n = 49) . | Nonsurvivors (n = 31) . | P value . |
|---|---|---|---|---|
| Age, median (25th-75th percentile), y | 26 (22-31) | 25 (22-31) | 27 (22-35) | .29 |
| Sex, n (%) | .52 | |||
| Male | 41 (51.3) | 25 (51) | 16 (51.6) | |
| Female | 37 (46.3) | 22 (44.9) | 15 (48.4) | |
| Unknown | 2 (2.5) | 2 (4.1) | 0 (0) | |
| Weight, median (25th-75th percentile), kg | 74.1 (63.6-91) | 73 (62.8-90.4) | 80 (65.8-93.2) | .36 |
| Height, mean ± SD, cm | 168.1 ± 11.2 | 167.8 ± 10.9 | 168.5 ± 11.8 | .81 |
| BMI, median (25th-75th percentile), kg/m2 | 26.4 (23.1-31) | 26.6 (22.8-30.5) | 28.2 (23.2-32) | .90 |
| Race, n (%) | .25 | |||
| Black | 66 (82.5) | 39 (79.6) | 27 (87.1) | |
| Hispanic | 1 (1.3) | 0 (0) | 1 (3.2) | |
| Middle Eastern/Northern African | 0 (0) | 0 (0) | 0 (0) | |
| Native American | 1 (1.3) | 0 (0) | 1 (3.2) | |
| White | 0 (0) | 0 (0) | 0 (0) | |
| Multiple | 6 (7.5) | 6 (12.2) | 0 (0) | |
| Other | 2 (2.5) | 1 (2) | 1 (3.2) | |
| Unknown | 3 (3.8) | 2 (4.1) | 1 (3.2) | |
| Support type, n (%) | — | |||
| Cardiac | 0 (0) | 0 (0) | 0 (0) | |
| eCPR | 0 (0) | 0 (0) | 0 (0) | |
| Pulmonary | 80 (100) | 49 (100) | 31 (100) | |
| Pre-ECLS arrest, n (%) | 8 (10) | 4 (8.2) | 4 (12.9) | .76 |
| Ventilator status, n (%) | .17 | |||
| Conventional | 64 (80) | 39 (79.6) | 25 (80.6) | |
| No ventilator | 1 (1.3) | 0 (0) | 1 (3.2) | |
| HFO | 3 (3.8) | 3 (6.1) | 0 (0) | |
| Other | 1 (1.3) | 0 (0) | 1 (3.2) | |
| Ventilator settings | ||||
| Respiratory rate (breaths per min), mean ± SD | 25 ± 8 | 24 ± 8 | 26 ± 7 | .33 |
| FiO2, median (25th-75th percentile), % | 100 (100-100) | 100 (100-100) | 100 (91-100) | .19 |
| PIP, median (25th-75th percentile), cm H2O | 36 (32-43) | 37 (31-46) | 35 (34-37) | .18 |
| PEEP, median (25th-75th percentile), cm H2O | 14 (10-17) | 14 (10-18) | 12 (10-14) | .25 |
| Mean airway pressure, median (25th-75th percentile), cm H2O | 23 (19-26) | 24 (20-28) | 20 (19-23) | .02 |
| Required hand-bagging, n (%) | 9 (11.3) | 5 (10.2) | 4 (12.9) | .36 |
| Laboratory values and vital signs | ||||
| pH, median (25th-75th percentile) | 7.28 (7.19-7.36) | 7.30 (7.20-7.37) | 7.25 (7.20-7.34) | .59 |
| pCO2, mean ± SD, mm Hg | 57 ± 19 | 56 ± 20 | 57 ± 18 | .85 |
| pO2, median (25th-75th percentile), mm Hg | 65 (55-79) | 66 (56-76) | 64 (55-82) | .96 |
| Serum bicarbonate, mean ± SD, mmol/L | 26 ± 7 | 26 ± 6 | 26 ±8 | .94 |
| SaO2, median (25th-75th percentile), % | 89 (81-94) | 89 (80-93) | 91 (82-95) | .88 |
| Lactate, median (25th-75th percentile), mmol/L | 2.4 (1.1-3.9) | 2.4 (1.1-3.9) | 2.5 (1.3-3.6) | .87 |
| Systolic blood pressure, mean ± SD, mm Hg | 116 ± 24 | 115 ± 25 | 116 ± 23 | .95 |
| Diastolic blood pressure, mean ± SD, mm Hg | 63 ± 17 | 63 ± 19 | 64 ± 14 | .88 |
| Mean arterial pressure, mean ± SD, mm Hg | 78 ± 19 | 78 ± 21 | 78 ± 18 | .88 |
| Pulse pressure, mean ± SD, mm Hg | 51 ± 18 | 51 ± 18 | 52 ± 18 | .87 |