Causes of IXZ dose reductions and suspension
| Cause of reduction . | n (%) . | Cause of suspension . | n (%) . |
|---|---|---|---|
| Gastrointestinal toxicity | 10 (25.6) | Withdrawal of consent | 15 (23) |
| Neuropathy | 1 (2.6) | Disease progression | 4 (10.3) |
| Neutropenia | 2 (5.1) | cGVHD | 1 (2.6) |
| Thrombocytopenia | 1 (2.6) | Gastrointestinal toxicity | 2 (5.2) |
| Infection | 1 (2.6) | Neutropenia | 1 (2.6) |
| Thrombocytopenia | 1 (2.6) | ||
| Neuropathy | 1 (2.6) | ||
| Liver toxicity | 1 (2.6) | ||
| Infection | 1 (2.6) | ||
| Hemolytic uremic syndrome | 1 (2.6) | ||
| Pericardial effusion | 1 (2.6) | ||
| Medical team decision | 1 (2.6) | ||
| Fever | 1 (2.6) |
| Cause of reduction . | n (%) . | Cause of suspension . | n (%) . |
|---|---|---|---|
| Gastrointestinal toxicity | 10 (25.6) | Withdrawal of consent | 15 (23) |
| Neuropathy | 1 (2.6) | Disease progression | 4 (10.3) |
| Neutropenia | 2 (5.1) | cGVHD | 1 (2.6) |
| Thrombocytopenia | 1 (2.6) | Gastrointestinal toxicity | 2 (5.2) |
| Infection | 1 (2.6) | Neutropenia | 1 (2.6) |
| Thrombocytopenia | 1 (2.6) | ||
| Neuropathy | 1 (2.6) | ||
| Liver toxicity | 1 (2.6) | ||
| Infection | 1 (2.6) | ||
| Hemolytic uremic syndrome | 1 (2.6) | ||
| Pericardial effusion | 1 (2.6) | ||
| Medical team decision | 1 (2.6) | ||
| Fever | 1 (2.6) |