Table 4.

Statistically significant deviations from HWE

PopulationLocusObserved heterozygosityExpected heterozygosityP valueWn
Black African HLA-A 0.935 0.942 .002 0.004 
Black African HLA-C 0.892 0.898 .000 0.002 
Black African HLA-DQB1 0.855 0.855 .050 0.000 
Coloured HLA-B 0.964 0.970 .021 0.012 
Indian/Asian HLA-A 0.889 0.905 .012 0.010 
Indian/Asian HLA-B 0.931 0.946 .000 0.013 
Indian/Asian HLA-DRB1 0.900 0.911 .003 0.009 
Indian/Asian HLA-DPB1 0.797 0.810 .003 0.007 
White HLA-DRB1 0.919 0.923 .042 0.001 
PopulationLocusObserved heterozygosityExpected heterozygosityP valueWn
Black African HLA-A 0.935 0.942 .002 0.004 
Black African HLA-C 0.892 0.898 .000 0.002 
Black African HLA-DQB1 0.855 0.855 .050 0.000 
Coloured HLA-B 0.964 0.970 .021 0.012 
Indian/Asian HLA-A 0.889 0.905 .012 0.010 
Indian/Asian HLA-B 0.931 0.946 .000 0.013 
Indian/Asian HLA-DRB1 0.900 0.911 .003 0.009 
Indian/Asian HLA-DPB1 0.797 0.810 .003 0.007 
White HLA-DRB1 0.919 0.923 .042 0.001 
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