Annualized rates of AEs (corrected for time on protocol in patient-years) during the HOVON 143 study
| Annualized rate of AE . | Frail based on age . | Frail based on impairments . | Ultrafrail . |
|---|---|---|---|
| Hematologic AE (all grades) | 0.45 | 0.23 | 0.48 |
| Non-hematologic AE (all grades) | 6.74 | 5.88 | 7.40 |
| Severe non-hematologic AE (grade ≥3) | 1.78 | 2.36 | 2.31 |
| Infections (all grades) | 0.46 | 0.77 | 0.74 |
| Severe infections (grade ≥3) | 0.07 | 0.36 | 0.42 |
| Annualized rate of AE . | Frail based on age . | Frail based on impairments . | Ultrafrail . |
|---|---|---|---|
| Hematologic AE (all grades) | 0.45 | 0.23 | 0.48 |
| Non-hematologic AE (all grades) | 6.74 | 5.88 | 7.40 |
| Severe non-hematologic AE (grade ≥3) | 1.78 | 2.36 | 2.31 |
| Infections (all grades) | 0.46 | 0.77 | 0.74 |
| Severe infections (grade ≥3) | 0.07 | 0.36 | 0.42 |