Table 4.

Outcome measures at baseline and 12 weeks for patients with slow-flow vascular malformations

OutcomeBaseline12 weeksP value
Platelets (n = 21) 250.0 (208-284) 261.0 (229-298) .345 
D-dimer (n = 20) 0.96 (0.28-3.10) 0.31 (0.20-1.35) .206 
Fibrinogen (n = 18) 289.6 (239-366) 333.5 (288-360) .093 
ESR (n = 14) 4.0 (2-6) 5.5 (2-7) .494 
Ferritin (n = 13) 46.0 (22-111) 64.0 (27.0-123.6) .241 
Pain score (n = 20) 4.0 (2-6) 2.0 (2-4) .216 
QOL total score (n = 24) 71.7 (59.8-79.9) 75.6 (67.9-86.4) .009 
QOL physical score (n = 24) 60.9 (46.9-70.3) 70.3 (54.7-82.8) .030 
QOL psychosocial score (n = 24) 78.3 (65.0-84.2) 80.0 (70.8-89.2) .022 
OutcomeBaseline12 weeksP value
Platelets (n = 21) 250.0 (208-284) 261.0 (229-298) .345 
D-dimer (n = 20) 0.96 (0.28-3.10) 0.31 (0.20-1.35) .206 
Fibrinogen (n = 18) 289.6 (239-366) 333.5 (288-360) .093 
ESR (n = 14) 4.0 (2-6) 5.5 (2-7) .494 
Ferritin (n = 13) 46.0 (22-111) 64.0 (27.0-123.6) .241 
Pain score (n = 20) 4.0 (2-6) 2.0 (2-4) .216 
QOL total score (n = 24) 71.7 (59.8-79.9) 75.6 (67.9-86.4) .009 
QOL physical score (n = 24) 60.9 (46.9-70.3) 70.3 (54.7-82.8) .030 
QOL psychosocial score (n = 24) 78.3 (65.0-84.2) 80.0 (70.8-89.2) .022 

Values are medians and the interquartile range. Data on D-dimer, ESR, and ferritin were log transformed due to nonnormal distributions of the raw data. Although transformed values were used to determine statistical significance, summary statistics of raw values are found in the table. Values in bold are statistically significant. Normal ranges are as follows: platelets (150-450 × 103/μL), D-dimer (<0.5 μg/mL), fibrinogen (200-400 mg/dL), ESR (0-20 mm/h), and ferritin (24-336 ng/mL). Pain scores range from 0 to 10. Values for QOL total, physical, and psychosocial range from 0 to 100.

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