Laboratory results and clinical outcomes of patients with AIC
| . | MT+, n = 25 . | MT–, n = 55 . | P value . |
|---|---|---|---|
| Coombs test | n = 12 | n = 28 | .03 |
| IgG only | 5 (42) | 14 (50) | |
| IgG and complement | 6 (50) | 3 (11) | |
| Complement only | 1 (10) | 4 (14) | |
| Negative | 0 (0) | 7 (25) | |
| IgG, mg/dL | 936 (687-1128) | 1370 (1012-1800) | .001 |
| Absolute lymphocyte count, ×103/μL | 0.8 (0.5-1.7) | 1.2 (0.7-2.52) | .14 |
| Absolute neutrophil count, ×103/μL | 4.3 (3.02-8.5) | 3.3 (2.05-6.28) | .09 |
| Nadir hemoglobin (g/dL) for AIHA and ES | n = 10 6.3 (5.48-8.2) | n = 20 6.1 (5.35-7.85) | .70 |
| Nadir platelet (×103/μL) for ITP and ES | n = 16 28.5 (8.5-95.50) | n = 36 18 (2-49.8) | .30 |
| Treatment requirement | 19 (76) | 48 (87) | .48 |
| No. of lines of treatment | n = 19 3 (1.5-3.5) | n = 48 3 (2-4) | .70 |
| Response | |||
| CR | 6/19 (32) | 24/48 (50) | .30 |
| Response | 11/19 (58) | 18/48 (38) | |
| No response | 2/19 (11) | 6/48 (12) | |
| Infection | |||
| Overall | 15 (60) | 33 (59) | 1 |
| Required hospitalization | 6 (24) | 12 (21) | .78 |
| . | MT+, n = 25 . | MT–, n = 55 . | P value . |
|---|---|---|---|
| Coombs test | n = 12 | n = 28 | .03 |
| IgG only | 5 (42) | 14 (50) | |
| IgG and complement | 6 (50) | 3 (11) | |
| Complement only | 1 (10) | 4 (14) | |
| Negative | 0 (0) | 7 (25) | |
| IgG, mg/dL | 936 (687-1128) | 1370 (1012-1800) | .001 |
| Absolute lymphocyte count, ×103/μL | 0.8 (0.5-1.7) | 1.2 (0.7-2.52) | .14 |
| Absolute neutrophil count, ×103/μL | 4.3 (3.02-8.5) | 3.3 (2.05-6.28) | .09 |
| Nadir hemoglobin (g/dL) for AIHA and ES | n = 10 6.3 (5.48-8.2) | n = 20 6.1 (5.35-7.85) | .70 |
| Nadir platelet (×103/μL) for ITP and ES | n = 16 28.5 (8.5-95.50) | n = 36 18 (2-49.8) | .30 |
| Treatment requirement | 19 (76) | 48 (87) | .48 |
| No. of lines of treatment | n = 19 3 (1.5-3.5) | n = 48 3 (2-4) | .70 |
| Response | |||
| CR | 6/19 (32) | 24/48 (50) | .30 |
| Response | 11/19 (58) | 18/48 (38) | |
| No response | 2/19 (11) | 6/48 (12) | |
| Infection | |||
| Overall | 15 (60) | 33 (59) | 1 |
| Required hospitalization | 6 (24) | 12 (21) | .78 |
Data are presented as n (%) and median (interquartile range). Statistically significant results are set in bold.