Table 4.

NIH ToolBox cognition battery scores for patients with and without SCI progression

TestNo SCI progression (n = 20)SCI progression (n = 8)
T-score at visit 1, median (IQR)T-score at visit 2, median (IQR)P valueT-score at visit 1, median (IQR)T-score at visit 2, median (IQR)P value
Picture vocabulary 51 (45, 59) 52.5 (43.5, 60.75) .548 57 (51.5, 63) 55.5 (45.75, 58.75) .624 
Oral reading recognition 55 (50, 59) 51 (47, 62.25) .835 56 (42.5,68.7) 53.3 (48.25, 64.75) .723 
List sorting working memory 48 (45, 53) 52 (45.5, 59.25) .116 53.5 (51.25, 58) 51 (38.5, 62) .233 
Picture sequence memory 52 (42, 59) 50.5 (43, 59.25) .938 56.5 (51, 60.75) 54.5 (47.75, 59.5) .279 
Flanker inhibitory control and attention 43 (36, 46) 46.5 (39, 59.25) .010 46.5 (38.25, 57.75) 43 (34.75, 58.75) .865 
Dimensional change cart sort test 44 (34, 60) 52 (45.75, 66.25) .016 55.5 (48.25, 68.25) 56.5 (51.5, 63.5) .833 
Pattern recognition 60 (43, 68) 56 (38.75, 71.5) .637 56.5 (42.75, 72.75) 67 (40, 79) .672 
Fluid cognition composite 51 (37, 60) 52.5 (38.25, 70.75) .048 60.5 (47.5, 65.5) 55.5 (41.25, 71.75) .438 
Crystalized cognition composite 52.5 (43.5, 60.75) 53 (44.5, 63) .575 60 (47, 65.5) 55.5 (48, 62.75) .686 
Total cognition composite 55 (40, 60) 57 (39.5, 64.75) .023 55 (53, 70.25) 56 (45, 74) .397 
TestNo SCI progression (n = 20)SCI progression (n = 8)
T-score at visit 1, median (IQR)T-score at visit 2, median (IQR)P valueT-score at visit 1, median (IQR)T-score at visit 2, median (IQR)P value
Picture vocabulary 51 (45, 59) 52.5 (43.5, 60.75) .548 57 (51.5, 63) 55.5 (45.75, 58.75) .624 
Oral reading recognition 55 (50, 59) 51 (47, 62.25) .835 56 (42.5,68.7) 53.3 (48.25, 64.75) .723 
List sorting working memory 48 (45, 53) 52 (45.5, 59.25) .116 53.5 (51.25, 58) 51 (38.5, 62) .233 
Picture sequence memory 52 (42, 59) 50.5 (43, 59.25) .938 56.5 (51, 60.75) 54.5 (47.75, 59.5) .279 
Flanker inhibitory control and attention 43 (36, 46) 46.5 (39, 59.25) .010 46.5 (38.25, 57.75) 43 (34.75, 58.75) .865 
Dimensional change cart sort test 44 (34, 60) 52 (45.75, 66.25) .016 55.5 (48.25, 68.25) 56.5 (51.5, 63.5) .833 
Pattern recognition 60 (43, 68) 56 (38.75, 71.5) .637 56.5 (42.75, 72.75) 67 (40, 79) .672 
Fluid cognition composite 51 (37, 60) 52.5 (38.25, 70.75) .048 60.5 (47.5, 65.5) 55.5 (41.25, 71.75) .438 
Crystalized cognition composite 52.5 (43.5, 60.75) 53 (44.5, 63) .575 60 (47, 65.5) 55.5 (48, 62.75) .686 
Total cognition composite 55 (40, 60) 57 (39.5, 64.75) .023 55 (53, 70.25) 56 (45, 74) .397 

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