Biochemical parameters of Townes mice treated with 1 × 1014 vg/kg rAAV8-mHPX or control vector
| . | rAAV8-mHPX . | rAAV8-Empty . | P value∗ . |
|---|---|---|---|
| ALT (U/L) | 111.0 (52.0-212.0) | 61.0 (30.0-85.7) | .07 |
| AST (U/L) | 81.0 (67.0-122.0) | 74.5 (36.2-80.7) | .09 |
| Creatinine (mg/dL) | 0.09 (0.09-0.12) | 0.11 (0.09-0.11) | .40 |
| Urea (mg/dL) | 58.0 (51.0-62.0) | 58.0 (53.0-64.7) | .53 |
| . | rAAV8-mHPX . | rAAV8-Empty . | P value∗ . |
|---|---|---|---|
| ALT (U/L) | 111.0 (52.0-212.0) | 61.0 (30.0-85.7) | .07 |
| AST (U/L) | 81.0 (67.0-122.0) | 74.5 (36.2-80.7) | .09 |
| Creatinine (mg/dL) | 0.09 (0.09-0.12) | 0.11 (0.09-0.11) | .40 |
| Urea (mg/dL) | 58.0 (51.0-62.0) | 58.0 (53.0-64.7) | .53 |
Results shown as median and interquartile range; n = 10-16 per group.
ALT, alanine transaminase; AST, aspartate aminotransferase.
Mann-Whitney U test.