Table 6.

Medication costs stratified by HU use

TotalHU treatedNot HU treatedP value
Median total medication costs per patient (IQR; range), $ 102.95 (15.55-531.98; 0.14-136 090.56) 672.64 (477.65-981.68; 5.42-91 373.85) 43.08 (10.73-205.06; 0.14-136 090.56) <.0001  
<18 y 88.10 (12.42-528.63; 0.14-136 090.56) 724.88 (535.25-1026.27; 5.42-91 373.85) 38.09 (8.61-151.11; 0.14-136 090.56) <.0001  
18-25 y 119.41 (13.91-442.67; 0.15-74 182.70) 562.01 (357.82-786.66; 8.19-68 696.45) 50.33 (10.05-303.76; 0.15-74 182.70) <.0001  
>25 y 166.83 (20.96-582.17; 0.27-68 244.55) 604.94 (387.64-980.08; 8.95-68 244.55) 54.51 (15.88-350.61; 0.27-57 560.64) <.0001  
Median total medication cost of ambulatory clinic visits per patient (IQR; range), $ 101.85 (13.70-531.86; 0.17-136 090.56) 658 (472.42-950.97; 2.30-91 373.85) 38.41 (8.93-201.34; 0.17-136 090.56) <.0001  
<18 y 77.54 (11.01-525.45; 0.19-136 090.56) 704.60 (521.82-1003.65; 5.42-91 373.85) 31.80 (6.94-140.38; 0.19-136 090.56) <.0001  
18-25 y 147.22 (12.63-444.66; 0.17-74 175.49) 525.41 (347.43-756.02; 2.30-68 696.45) 65.16 (7.30-324.90; 0.17-74 175.49) <.0001  
>25 y 179.32 (19.69-588.21; 0.32-68 239.59) 597.64 (392.09-959.81; 19.23-68 239.59) 59.05 (14.57-350.94; 0.32-57 560.64) <.0001  
Median total medication cost of ED visits per patient (IQR; range), $ 7.62 (2.94-14.82; 0.01-701.54) 9.15 (3.75-15.16; 0.13-86.14) 7.15 (2.80-14.48; 0.01-701.54) .0547  
<18 y 6.74 (2.37-13.18; 0.01-701.54) 9.01 (3.77-14.58; 0.13-71.35) 6.10 (2.03-12.49; 0.01-701.54) .0143  
18-25 y 8.03 (3.05-14.24; 0.14-72) 9 (3.47-14.56; 0.87-41.47) 7.40 (2.98-14.17; 0.14-72) .4074  
>25 y 9.35 (3.64-18.11; 0.25-286.34) 9.47 (3.73-17.74; 0.25-86.14) 9.31 (3.63-18.20; 0.26-286.34) .9995  
Median total medication cost of admissions per patient (IQR; range), $ 30.93 (11.46-78.02; 0.19-3867.98) 44.17 (16.61-103.68; 0.19-775.62) 27.52 (10.83-68.61; 0.23-3867.98) .0118  
<18 years of age 33.86 (12.78-78.02; 0.79-511.12) 45.96 (15.43-111.70; 1.62-511.12) 28.73 (12.38-65.31; 0.79-281.92) .0127  
18-25 years of age 31.80 (13.25-81; 2-1247.52) 43.66 (17.88-117.20; 5.67-775.62) 27.37 (11.52-70.30; 2-1247.52) .2388  
>25 years of age 24.49 (9.34-72.18; 0.19-3867.98) 25.78 (16.61-90; 0.19-215.01) 24.49 (7.40-68.64; 0.23-3867.98) .7472  
TotalHU treatedNot HU treatedP value
Median total medication costs per patient (IQR; range), $ 102.95 (15.55-531.98; 0.14-136 090.56) 672.64 (477.65-981.68; 5.42-91 373.85) 43.08 (10.73-205.06; 0.14-136 090.56) <.0001  
<18 y 88.10 (12.42-528.63; 0.14-136 090.56) 724.88 (535.25-1026.27; 5.42-91 373.85) 38.09 (8.61-151.11; 0.14-136 090.56) <.0001  
18-25 y 119.41 (13.91-442.67; 0.15-74 182.70) 562.01 (357.82-786.66; 8.19-68 696.45) 50.33 (10.05-303.76; 0.15-74 182.70) <.0001  
>25 y 166.83 (20.96-582.17; 0.27-68 244.55) 604.94 (387.64-980.08; 8.95-68 244.55) 54.51 (15.88-350.61; 0.27-57 560.64) <.0001  
Median total medication cost of ambulatory clinic visits per patient (IQR; range), $ 101.85 (13.70-531.86; 0.17-136 090.56) 658 (472.42-950.97; 2.30-91 373.85) 38.41 (8.93-201.34; 0.17-136 090.56) <.0001  
<18 y 77.54 (11.01-525.45; 0.19-136 090.56) 704.60 (521.82-1003.65; 5.42-91 373.85) 31.80 (6.94-140.38; 0.19-136 090.56) <.0001  
18-25 y 147.22 (12.63-444.66; 0.17-74 175.49) 525.41 (347.43-756.02; 2.30-68 696.45) 65.16 (7.30-324.90; 0.17-74 175.49) <.0001  
>25 y 179.32 (19.69-588.21; 0.32-68 239.59) 597.64 (392.09-959.81; 19.23-68 239.59) 59.05 (14.57-350.94; 0.32-57 560.64) <.0001  
Median total medication cost of ED visits per patient (IQR; range), $ 7.62 (2.94-14.82; 0.01-701.54) 9.15 (3.75-15.16; 0.13-86.14) 7.15 (2.80-14.48; 0.01-701.54) .0547  
<18 y 6.74 (2.37-13.18; 0.01-701.54) 9.01 (3.77-14.58; 0.13-71.35) 6.10 (2.03-12.49; 0.01-701.54) .0143  
18-25 y 8.03 (3.05-14.24; 0.14-72) 9 (3.47-14.56; 0.87-41.47) 7.40 (2.98-14.17; 0.14-72) .4074  
>25 y 9.35 (3.64-18.11; 0.25-286.34) 9.47 (3.73-17.74; 0.25-86.14) 9.31 (3.63-18.20; 0.26-286.34) .9995  
Median total medication cost of admissions per patient (IQR; range), $ 30.93 (11.46-78.02; 0.19-3867.98) 44.17 (16.61-103.68; 0.19-775.62) 27.52 (10.83-68.61; 0.23-3867.98) .0118  
<18 years of age 33.86 (12.78-78.02; 0.79-511.12) 45.96 (15.43-111.70; 1.62-511.12) 28.73 (12.38-65.31; 0.79-281.92) .0127  
18-25 years of age 31.80 (13.25-81; 2-1247.52) 43.66 (17.88-117.20; 5.67-775.62) 27.37 (11.52-70.30; 2-1247.52) .2388  
>25 years of age 24.49 (9.34-72.18; 0.19-3867.98) 25.78 (16.61-90; 0.19-215.01) 24.49 (7.40-68.64; 0.23-3867.98) .7472  

Wilcoxon rank sum test with continuity correction.

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