Current portfolio of CFC and procoagulant medications provided by the Brazilian national program on IBDs
| CFC/procoagulant . | Target patient population . |
|---|---|
| Recombinant factor VIII | Hemophilia A |
| Plasma-derived factor VIII | Hemophilia A |
| Plasma-derived factor IX | Hemophilia B |
| Plasma-derived VWF | VWD |
| Emicizumab | Hemophilia A with inhibitors |
| Prothrombin complex concentrate | Deficiency of factors II, VII, IX, and X |
| Activated prothrombin complex concentrate | Hemophilia A with inhibitors |
| Recombinant factor VII activated | Hemophilia A with inhibitors, factor VII deficiency, Glanzmann thrombasthenia |
| Plasma-derived factor XIII | Factor XIII deficiency |
| Plasma-derived fibrinogen | Hypofibrinogenemia and afibrinogenemia |
| Desmopressin acetate | VWD, mild/moderate hemophilia A |
| Tranexamic acid, oral | All patients, when indicated |
| CFC/procoagulant . | Target patient population . |
|---|---|
| Recombinant factor VIII | Hemophilia A |
| Plasma-derived factor VIII | Hemophilia A |
| Plasma-derived factor IX | Hemophilia B |
| Plasma-derived VWF | VWD |
| Emicizumab | Hemophilia A with inhibitors |
| Prothrombin complex concentrate | Deficiency of factors II, VII, IX, and X |
| Activated prothrombin complex concentrate | Hemophilia A with inhibitors |
| Recombinant factor VII activated | Hemophilia A with inhibitors, factor VII deficiency, Glanzmann thrombasthenia |
| Plasma-derived factor XIII | Factor XIII deficiency |
| Plasma-derived fibrinogen | Hypofibrinogenemia and afibrinogenemia |
| Desmopressin acetate | VWD, mild/moderate hemophilia A |
| Tranexamic acid, oral | All patients, when indicated |
VWF, von Willebrand factor.