Table 3.

DW-MRI disease patterns

Disease patternDescription
Diffuse Diffuse decreased signal intensity in T1-weighted sequences and increased signal intensity in T2-weighted, STIR, and high b-value DW sequences, with ADC values >600 to 700 μm2/s 
Micronodular Widespread nodular areas <5 mm with preserved normal marrow in between 
Focal Lesions ≥5 mm with decreased signal in T1-weighted sequences, increased signal in T2-weighted and STIR sequences, hyperintense to background muscle in high b-value images, compatible ADC values (600-1400 μm2/s) 
Focal on diffuse Coexistence of focal and DD 
Disease patternDescription
Diffuse Diffuse decreased signal intensity in T1-weighted sequences and increased signal intensity in T2-weighted, STIR, and high b-value DW sequences, with ADC values >600 to 700 μm2/s 
Micronodular Widespread nodular areas <5 mm with preserved normal marrow in between 
Focal Lesions ≥5 mm with decreased signal in T1-weighted sequences, increased signal in T2-weighted and STIR sequences, hyperintense to background muscle in high b-value images, compatible ADC values (600-1400 μm2/s) 
Focal on diffuse Coexistence of focal and DD 

Adapted from Messiou et al.82 

STIR, short tau inversion recovery.

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