Organ involvement in hemochromatosis
Organ . | Manifestations . | Complications . |
|---|---|---|
| Liver | Enzyme alterations | Fibrosis, cirrhosis, hepatocellular carcinoma* |
| Heart | Arrhythmia, failure | Cardiomyopathy |
| Pancreas | Hyperglycemia | Diabetes mellitus |
| Pituitary | Decreased libido, impotence in men; amenorrhea in women | Hypogonadism |
| Thyroid gland | Decreased thyroid hormone | Hypothyroidism |
| Joints | Arthralgia | Arthropathy |
| Skin | Pigmentation | None |
Organ . | Manifestations . | Complications . |
|---|---|---|
| Liver | Enzyme alterations | Fibrosis, cirrhosis, hepatocellular carcinoma* |
| Heart | Arrhythmia, failure | Cardiomyopathy |
| Pancreas | Hyperglycemia | Diabetes mellitus |
| Pituitary | Decreased libido, impotence in men; amenorrhea in women | Hypogonadism |
| Thyroid gland | Decreased thyroid hormone | Hypothyroidism |
| Joints | Arthralgia | Arthropathy |
| Skin | Pigmentation | None |
All the possible hemochromatosis complications are listed; however, patients presenting with all these clinical findings are exceptional, and most have nonspecific symptoms, or abnormalities of iron parameters and of liver enzymes.
Increased risk in cirrhotic patients.