Table 3.

Achievement of complete remission according to the NPM1/FLT3 ITD mutation status



FLT3 ITD negative, n = 203

FLT3 ITD positive, n = 97
Remission
NPM1 mutated, n = 86; no. of patients (%)
NPM1 unmutated, n = 117; no. of patients (%)
NPM1 mutated, n = 59; no. of patients (%)
NPM1 unmutated, n = 38; no. of patients (%)
CR   74 (86)   78 (68.5)   37 (63)   28 (76)  
RD   2 (2)   23 (20)   14 (24)   7 (19)  
ED/HD   10 (12)   13 (11.5)   8 (13)   2 (5)  
Missing
 
0
 
3
 
0
 
1
 


FLT3 ITD negative, n = 203

FLT3 ITD positive, n = 97
Remission
NPM1 mutated, n = 86; no. of patients (%)
NPM1 unmutated, n = 117; no. of patients (%)
NPM1 mutated, n = 59; no. of patients (%)
NPM1 unmutated, n = 38; no. of patients (%)
CR   74 (86)   78 (68.5)   37 (63)   28 (76)  
RD   2 (2)   23 (20)   14 (24)   7 (19)  
ED/HD   10 (12)   13 (11.5)   8 (13)   2 (5)  
Missing
 
0
 
3
 
0
 
1
 

CR indicates complete remission; RD, resistant disease; and ED/HD, early/hypoplastic death.

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