Achievement of complete remission according to the NPM1/FLT3 ITD mutation status
. | FLT3 ITD negative, n = 203 . | . | FLT3 ITD positive, n = 97 . | . | ||
---|---|---|---|---|---|---|
Remission . | NPM1 mutated, n = 86; no. of patients (%) . | NPM1 unmutated, n = 117; no. of patients (%) . | NPM1 mutated, n = 59; no. of patients (%) . | NPM1 unmutated, n = 38; no. of patients (%) . | ||
CR | 74 (86) | 78 (68.5) | 37 (63) | 28 (76) | ||
RD | 2 (2) | 23 (20) | 14 (24) | 7 (19) | ||
ED/HD | 10 (12) | 13 (11.5) | 8 (13) | 2 (5) | ||
Missing | 0 | 3 | 0 | 1 |
. | FLT3 ITD negative, n = 203 . | . | FLT3 ITD positive, n = 97 . | . | ||
---|---|---|---|---|---|---|
Remission . | NPM1 mutated, n = 86; no. of patients (%) . | NPM1 unmutated, n = 117; no. of patients (%) . | NPM1 mutated, n = 59; no. of patients (%) . | NPM1 unmutated, n = 38; no. of patients (%) . | ||
CR | 74 (86) | 78 (68.5) | 37 (63) | 28 (76) | ||
RD | 2 (2) | 23 (20) | 14 (24) | 7 (19) | ||
ED/HD | 10 (12) | 13 (11.5) | 8 (13) | 2 (5) | ||
Missing | 0 | 3 | 0 | 1 |
CR indicates complete remission; RD, resistant disease; and ED/HD, early/hypoplastic death.