Table 5.

Engraftment of CD13+ and CD13- fractions of AML in NOD/SCID mice


Sample no. and dose/mouse

No. mice with AML/no. mice injected
CD13+ fraction  
   1*  
      5.3 × 105  3/4  
      3.5 × 106  3/3  
   3   
      5.0 × 105  2/2  
   6   
      1.4 × 106  2/3  
   7   
      5.0 × 106  2/2  
      3.5 × 106  1/2  
   9   
      3.6 × 106  2/2  
      8.3 × 106  2/2  
   13   
      1.5 × 106  3/3  
CD13- fraction  
   1*  
      5.3 × 105  0/3  
   3   
      5.0 × 105  4/4  
      3.0 × 106  3/3  
   6   
      1.4 × 106  0/2  
      2.7 × 106  1/2  
   7   
      5.0 × 106  1/2  
      3.5 × 106  4/4  
   9   
      3.6 × 106  0/3  
   13   
      1.5 × 106
 
1/2
 

Sample no. and dose/mouse

No. mice with AML/no. mice injected
CD13+ fraction  
   1*  
      5.3 × 105  3/4  
      3.5 × 106  3/3  
   3   
      5.0 × 105  2/2  
   6   
      1.4 × 106  2/3  
   7   
      5.0 × 106  2/2  
      3.5 × 106  1/2  
   9   
      3.6 × 106  2/2  
      8.3 × 106  2/2  
   13   
      1.5 × 106  3/3  
CD13- fraction  
   1*  
      5.3 × 105  0/3  
   3   
      5.0 × 105  4/4  
      3.0 × 106  3/3  
   6   
      1.4 × 106  0/2  
      2.7 × 106  1/2  
   7   
      5.0 × 106  1/2  
      3.5 × 106  4/4  
   9   
      3.6 × 106  0/3  
   13   
      1.5 × 106
 
1/2
 

ND indicates not determined.

*

Denotes that mice used as a host for this leukemia were NOD/SCID-β2m-/- mice

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