Comparative patient characteristics in the pre- and post-HAART eras
Characteristic . | Before HAART . | After HAART . | P . |
|---|---|---|---|
| Sex, male (%) | 263 (88) | 151 (81) | .03 |
| Median age, y (range) | 38 (22-67) | 37 (18-66) | .4 |
| Stage 3-4, no. (%) | 192 (64) | 111 (59) | .3 |
| At least 2 extranodal sites, no. (%) | 102 (34) | 65 (34) | .9 |
| Performance status at least 2, no. (%) | 57 (19) | 25 (13) | .1 |
| LDH level above normal, no. (%) | 171 (57) | 97 (52) | .2 |
| aaIPI score at least 2, no. (%) | 145 (49) | 82 (44) | .3 |
| HIV score, no. (%) | |||
| 0 | 132 (44) | 86 (46) | — |
| 1 | 95 (32) | 82 (43) | — |
| 2-3 | 71 (24) | 19 (11) | < .001 |
| Time between HIV and lymphoma, mo (range) | 49 (0-156) | 62 (0-170) | .03 |
| AIDS prior to NHL, no. (%) | 65 (21) | 34 (18) | .3 |
| CD4+ cells | |||
| Median count per mm3 (range) | 114 (1-1005) | 143 (0-1584) | < .001 |
| Count less than 100/mm3, no. (%) | 135 (45) | 54 (29) | < .001 |
| NHL subtypes, no. (%) | |||
| Diffuse large B cell | 153 (51) | 113 (60) | — |
| Immunoblastic | 62 (21) | 23 (12) | — |
| Burkitt | 74 (25) | 24 (13) | — |
| Other large cells | 9 (3) | 30 (16) | .002 |
Characteristic . | Before HAART . | After HAART . | P . |
|---|---|---|---|
| Sex, male (%) | 263 (88) | 151 (81) | .03 |
| Median age, y (range) | 38 (22-67) | 37 (18-66) | .4 |
| Stage 3-4, no. (%) | 192 (64) | 111 (59) | .3 |
| At least 2 extranodal sites, no. (%) | 102 (34) | 65 (34) | .9 |
| Performance status at least 2, no. (%) | 57 (19) | 25 (13) | .1 |
| LDH level above normal, no. (%) | 171 (57) | 97 (52) | .2 |
| aaIPI score at least 2, no. (%) | 145 (49) | 82 (44) | .3 |
| HIV score, no. (%) | |||
| 0 | 132 (44) | 86 (46) | — |
| 1 | 95 (32) | 82 (43) | — |
| 2-3 | 71 (24) | 19 (11) | < .001 |
| Time between HIV and lymphoma, mo (range) | 49 (0-156) | 62 (0-170) | .03 |
| AIDS prior to NHL, no. (%) | 65 (21) | 34 (18) | .3 |
| CD4+ cells | |||
| Median count per mm3 (range) | 114 (1-1005) | 143 (0-1584) | < .001 |
| Count less than 100/mm3, no. (%) | 135 (45) | 54 (29) | < .001 |
| NHL subtypes, no. (%) | |||
| Diffuse large B cell | 153 (51) | 113 (60) | — |
| Immunoblastic | 62 (21) | 23 (12) | — |
| Burkitt | 74 (25) | 24 (13) | — |
| Other large cells | 9 (3) | 30 (16) | .002 |
For pre-HAART patients, n = 298; for post-HAART patients, n = 187.
— indicates not applicable.