Multivariate risk factor analysis for overall long-term survival
. | HR . | 95% CI . | P . |
|---|---|---|---|
| Advanced stage at HSCT | |||
| Cohort I | 2.67 | 1.18-5.96 | .018 |
| Cohort II | 0.89 | 0.49-1.59 | NS |
| No. of NOD2/CARD15 variants | |||
| Cohort I | |||
| Wild type | 1.0 | NA | Overall .001 |
| 1 variant | 2.8 | 1.30-5.87 | .008 |
| 2 or more variants | 3.9 | 1.47-10.46 | .007 |
| Cohort II | |||
| Wild type | 1.0 | NA | Overall .012 |
| 1 variant | 1.2 | 0.63-2.12 | NS |
| 2 or more variants | 2.7 | 1.39-5.1 | .003 |
. | HR . | 95% CI . | P . |
|---|---|---|---|
| Advanced stage at HSCT | |||
| Cohort I | 2.67 | 1.18-5.96 | .018 |
| Cohort II | 0.89 | 0.49-1.59 | NS |
| No. of NOD2/CARD15 variants | |||
| Cohort I | |||
| Wild type | 1.0 | NA | Overall .001 |
| 1 variant | 2.8 | 1.30-5.87 | .008 |
| 2 or more variants | 3.9 | 1.47-10.46 | .007 |
| Cohort II | |||
| Wild type | 1.0 | NA | Overall .012 |
| 1 variant | 1.2 | 0.63-2.12 | NS |
| 2 or more variants | 2.7 | 1.39-5.1 | .003 |
The number of NOD2/CARD15 variants is the main significant risk factor for OS in multivariate analysis of both cohorts.
NA indicates not applicable; NS, not significant.