Clinical and laboratory characteristics
Characteristic . | Patients analyzed, no. (%) . | Patients not analyzed, no. (%) . | P . |
|---|---|---|---|
| Sex | NS | ||
| Male | 37 (58.7) | 49 (69) | |
| Female | 26 (41.3) | 22 (31) | |
| Age | NS | ||
| 1-9 years | 25 (39.7) | 30 (42.3) | |
| At least 10 years | 38 (60.3) | 41 (57.7) | |
| CNS* | NS | ||
| Positive | 3 (4.9) | 2 (2.9) | |
| Negative | 58 (95.1) | 68 (97.1) | |
| BM | NS | ||
| Positive | 0 (0) | 0 (0) | |
| Negative | 63 (100) | 71 (100) | |
| Bone | NS | ||
| Positive | 5 (7.9) | 2 (2.8) | |
| Negative | 58 (92.1) | 69 (97.2) | |
| Stage | NS | ||
| 1 | 12 (19.0) | 20 (28.2) | |
| 2 | 20 (31.7) | 24 (33.8) | |
| 3 | 29 (46.0) | 25 (35.2) | |
| 4 | 2 (3.2) | 2 (2.8) | |
| LDH* | .01 | ||
| Less than 500 U/L | 47 (77.0) | 65 (92.9) | |
| At least 500 U/L | 14 (23.0) | 5 (7.1) | |
| Extranodal involvement | NS | ||
| No | 10 (15.9) | 20 (28.2) | |
| Yes | 53 (84.1) | 51 (71.8) |
Characteristic . | Patients analyzed, no. (%) . | Patients not analyzed, no. (%) . | P . |
|---|---|---|---|
| Sex | NS | ||
| Male | 37 (58.7) | 49 (69) | |
| Female | 26 (41.3) | 22 (31) | |
| Age | NS | ||
| 1-9 years | 25 (39.7) | 30 (42.3) | |
| At least 10 years | 38 (60.3) | 41 (57.7) | |
| CNS* | NS | ||
| Positive | 3 (4.9) | 2 (2.9) | |
| Negative | 58 (95.1) | 68 (97.1) | |
| BM | NS | ||
| Positive | 0 (0) | 0 (0) | |
| Negative | 63 (100) | 71 (100) | |
| Bone | NS | ||
| Positive | 5 (7.9) | 2 (2.8) | |
| Negative | 58 (92.1) | 69 (97.2) | |
| Stage | NS | ||
| 1 | 12 (19.0) | 20 (28.2) | |
| 2 | 20 (31.7) | 24 (33.8) | |
| 3 | 29 (46.0) | 25 (35.2) | |
| 4 | 2 (3.2) | 2 (2.8) | |
| LDH* | .01 | ||
| Less than 500 U/L | 47 (77.0) | 65 (92.9) | |
| At least 500 U/L | 14 (23.0) | 5 (7.1) | |
| Extranodal involvement | NS | ||
| No | 10 (15.9) | 20 (28.2) | |
| Yes | 53 (84.1) | 51 (71.8) |
The clinical characteristics of the patients analyzed in this study were compared to the rest of patients with the diagnosis DLBCL from the 2 consecutive Berlin-Frankfurt-Münster Group Multicenter Trials NHL-BFM 90 and 95 that were not included in this study (Fisher exact or χ2 test). The number of patients for which the clinical information was available and the percentage is shown.
CNS indicates central nervous system; NS indicates not significant.
Data not available for all patients.