Table 3.

Clinical and laboratory characteristics of pediatric GCB and non-GCB DLBCL


Characteristic

GCB, no. (%)

non-GCB, no. (%)

P
Sex    NS  
    Male   25 (58.1)   5 (55.6)   
    Female   18 (41.9)   4 (44.4)   
Age    NS  
    1-9 years   18 (41.9)   2 (22.2)   
    At least 10 years   25 (58.1)   7 (77.8)   
CNS*    NS  
    Positive   1 (2.3)   1 (11.1)   
    Negative   40 (93.0)   8 (88.9)   
BM    NS  
    Positive   0 (0)   0 (0)   
    Negative   43 (100)   9 (100)   
Bone    NS  
    Positive   4 (9.3)   0 (0)   
    Negative   39 (90.7)   9 (100)   
Stage    NS  
    1   9 (20.9)   2 (22.2)   
    2   12 (27.9)   2 (22.2)   
    3   21 (48.8)   5 (55.6)   
    4   1 (2.3)   0 (0)   
LDH*    NS  
    Less than 500 U/L   33 (76.7)   5 (55.6)   
    At least 500 U/L   9 (20.9)   3 (33.3)   
Extranodal involvement    NS  
    No   37 (86.0)   6 (14.0)   
    Yes
 
9 (100)
 
0 (0)
 

 

Characteristic

GCB, no. (%)

non-GCB, no. (%)

P
Sex    NS  
    Male   25 (58.1)   5 (55.6)   
    Female   18 (41.9)   4 (44.4)   
Age    NS  
    1-9 years   18 (41.9)   2 (22.2)   
    At least 10 years   25 (58.1)   7 (77.8)   
CNS*    NS  
    Positive   1 (2.3)   1 (11.1)   
    Negative   40 (93.0)   8 (88.9)   
BM    NS  
    Positive   0 (0)   0 (0)   
    Negative   43 (100)   9 (100)   
Bone    NS  
    Positive   4 (9.3)   0 (0)   
    Negative   39 (90.7)   9 (100)   
Stage    NS  
    1   9 (20.9)   2 (22.2)   
    2   12 (27.9)   2 (22.2)   
    3   21 (48.8)   5 (55.6)   
    4   1 (2.3)   0 (0)   
LDH*    NS  
    Less than 500 U/L   33 (76.7)   5 (55.6)   
    At least 500 U/L   9 (20.9)   3 (33.3)   
Extranodal involvement    NS  
    No   37 (86.0)   6 (14.0)   
    Yes
 
9 (100)
 
0 (0)
 

 

The clinical characteristics were compared between the GCB and non-GCB subgroups. The number of patients of which the clinical information was available and the percentage is shown (Fisher exact or χ2 test).

*

Data not available for all patients.

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