Pesticide use among 180 cases of aplastic anemia and 770 controls in Khonkaen (phase 2 data only)
. | Cases . | . | Controls . | . | Relative risk estimate* . | . | |||
|---|---|---|---|---|---|---|---|---|---|
| Pesticide . | No. . | % . | No. . | % . | Crude . | Multivariate†(95% CI) . | |||
| Organophosphates‡ | 21 | 12 | 32 | 4 | 3.0 | 2.1 (1.1-4.2) | |||
| Applied by subject | 15 | 8 | 16 | 2 | 4.4 | 2.9 (1.3-6.9) | |||
| At least 4 days' total exposure | 17 | 9 | 26 | 3 | 3.0 | 2.1 (1.0-4.4) | |||
| DDT | 5 | 3 | 4 | 0.5 | 5.5 | 6.7 (1.5-30) | |||
| Applied by subject | 5 | 3 | 4 | 0.5 | 5.5 | — | |||
| At least 4 days' total exposure | 5 | 3 | 4 | 0.5 | 5.5 | — | |||
| Carbamates§ | 8 | 4 | 3 | 0.4 | 12 | 7.4 (1.7-31) | |||
| Applied by subject | 7 | 4 | 2 | 0.3 | — | — | |||
| At least 4 days' total exposure | 6 | 3 | 1 | 0.1 | — | — | |||
| Paraquat | 12 | 7 | 24 | 3 | 2.2 | 2.3 (1.0-5.1) | |||
| Applied by subject | 7 | 4 | 17 | 2 | 1.8 | 1.7 (0.6-4.7) | |||
| At least 4 days' total exposure | 7 | 4 | 20 | 3 | 1.6 | 1.9 (0.7-4.9) | |||
| Other occupational pesticides∥ | 11 | 6 | 32 | 4 | 1.5 | 1.0 (0.4-2.2) | |||
| Applied by subject | 6 | 3 | 18 | 2 | 1.5 | 0.7 (0.2-2.2) | |||
| At least 4 days' total exposure | 9 | 5 | 24 | 3 | 1.6 | 1.1 (0.4-2.7) | |||
| Any household pesticides | 64 | 36 | 238 | 31 | 1.2 | 1.3 (0.9-1.9) | |||
. | Cases . | . | Controls . | . | Relative risk estimate* . | . | |||
|---|---|---|---|---|---|---|---|---|---|
| Pesticide . | No. . | % . | No. . | % . | Crude . | Multivariate†(95% CI) . | |||
| Organophosphates‡ | 21 | 12 | 32 | 4 | 3.0 | 2.1 (1.1-4.2) | |||
| Applied by subject | 15 | 8 | 16 | 2 | 4.4 | 2.9 (1.3-6.9) | |||
| At least 4 days' total exposure | 17 | 9 | 26 | 3 | 3.0 | 2.1 (1.0-4.4) | |||
| DDT | 5 | 3 | 4 | 0.5 | 5.5 | 6.7 (1.5-30) | |||
| Applied by subject | 5 | 3 | 4 | 0.5 | 5.5 | — | |||
| At least 4 days' total exposure | 5 | 3 | 4 | 0.5 | 5.5 | — | |||
| Carbamates§ | 8 | 4 | 3 | 0.4 | 12 | 7.4 (1.7-31) | |||
| Applied by subject | 7 | 4 | 2 | 0.3 | — | — | |||
| At least 4 days' total exposure | 6 | 3 | 1 | 0.1 | — | — | |||
| Paraquat | 12 | 7 | 24 | 3 | 2.2 | 2.3 (1.0-5.1) | |||
| Applied by subject | 7 | 4 | 17 | 2 | 1.8 | 1.7 (0.6-4.7) | |||
| At least 4 days' total exposure | 7 | 4 | 20 | 3 | 1.6 | 1.9 (0.7-4.9) | |||
| Other occupational pesticides∥ | 11 | 6 | 32 | 4 | 1.5 | 1.0 (0.4-2.2) | |||
| Applied by subject | 6 | 3 | 18 | 2 | 1.5 | 0.7 (0.2-2.2) | |||
| At least 4 days' total exposure | 9 | 5 | 24 | 3 | 1.6 | 1.1 (0.4-2.7) | |||
| Any household pesticides | 64 | 36 | 238 | 31 | 1.2 | 1.3 (0.9-1.9) | |||
— indicates not calculated.
Relative to nonexposure to the pesticide under consideration
The following factors were included in the model: age, sex, residential location, year of interview (continuous term), pesticide use, exposure to ducks, animal fertilizer use, consumption of nonbottled water. Statistically significant estimates are italicized
Methyl parathion (19 cases, 32 controls), omethoate (1 case), methalamidophos (1 case)
Methomyl (6 cases, 1 control), carbofuran (2, 2), carbaryl (1, 0)
Glyphosate (3 cases, 23 controls), karate (3, 0), spark (1, 1), 2,4-D (1, 1), spato (1, 0), filatan (1, 0), supercorn (1, 0), endrin (0, 1), unspecified insecticide (2, 9), unspecified rodenticide (2, 1), unspecified fungicide (0, 1), unspecified herbicide (0, 1)