Table 1.

Total fetal liver hematopoietic progenitors


Genotype

CFU-MIX, × 105

BFU-E, × 103

CFU-E, × 105

CFU-GM, × 105

CFU-MEG, × 103
WT   1.23 ± 0.003   47 ± 0.27   4.0 ± 0.005   2.5 ± 0.002   6.1 ± 0.03  
p85β+/-  1.37 ± 0.002   41 ± 0.18   4.2 ± 0.003   3.0 ± 0.005   6.8 ± 0.05  
p85α-/-  0.6 ± 0.005   20 ± 0.1*  3.0 ± 0.001*  1.5 ± 0.001*  3.66 ± 0.06* 
p85α-/-; p85β+/-
 
0.1 ± 0.001*
 
2.8 ± 0.15*
 
1.1 ± 0.001*
 
0.21 ± 0.001*
 
0.7 ± 0.04*
 

Genotype

CFU-MIX, × 105

BFU-E, × 103

CFU-E, × 105

CFU-GM, × 105

CFU-MEG, × 103
WT   1.23 ± 0.003   47 ± 0.27   4.0 ± 0.005   2.5 ± 0.002   6.1 ± 0.03  
p85β+/-  1.37 ± 0.002   41 ± 0.18   4.2 ± 0.003   3.0 ± 0.005   6.8 ± 0.05  
p85α-/-  0.6 ± 0.005   20 ± 0.1*  3.0 ± 0.001*  1.5 ± 0.001*  3.66 ± 0.06* 
p85α-/-; p85β+/-
 
0.1 ± 0.001*
 
2.8 ± 0.15*
 
1.1 ± 0.001*
 
0.21 ± 0.001*
 
0.7 ± 0.04*
 

Data are presented as the mean plus or minus the standard error of the mean.

*

P < .02 compared with WT

P < .05 compared with p85α-/-

Close Modal

or Create an Account

Close Modal
Close Modal