Table 1.

Average number of colonies in healthy controls and in CML patients and reduction in the colony-forming ability of healthy and CML myeloid progenitors after treatment with IM, LMB, or their combination




No treatment

IM

LMB

IM + LMB
Healthy controls     
   Colonies, no.   105   73   44   51  
   Reduction, % (95% CI)   —   40 (29-49)   61 (53-68)   59 (41-72)  
Patients with CML     
   Colonies, no.   91   62   21   13  
   Reduction, % (95% CI)
 

 
37 (33-40)
 
79 (78-81)
 
88 (82-92)
 



No treatment

IM

LMB

IM + LMB
Healthy controls     
   Colonies, no.   105   73   44   51  
   Reduction, % (95% CI)   —   40 (29-49)   61 (53-68)   59 (41-72)  
Patients with CML     
   Colonies, no.   91   62   21   13  
   Reduction, % (95% CI)
 

 
37 (33-40)
 
79 (78-81)
 
88 (82-92)
 

— indicates not applicable.

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