Table 5.

Multivariate analysis for relative risk of death




Relative risk of death (95% CI)

P
HLA-identical sibling BM   
   G-CSF+ within 7 days after transplantation vs no G-CSF*  1.11 (0.90-1.36)   .35  
   Age   1.02 (1.01-1.03)   .004  
   KPS more than 80* vs less than 80%   1.34 (1.10-1.64)   .004  
   Disease stage at transplantation    
      Intermediate vs early*  1.99 (1.57-2.52)   < .001  
      Advanced vs early*  2.93 (2.35-3.65)   < .001  
HLA-identical sibling PBSCs   
   G-CSF+ within 7 days after transplantation vs no G-CSF*  1.07 (0.84-1.37)   .57  
   Age   1.02 (1.01-1.03)   .003  
   KPS more than 80* vs less than 80%   1.66 (1.29-2.13)   < .001  
   Disease stage at transplantation    
      Intermediate vs early*  1.60 (1.14-2.24)   .006  
      Advanced vs early*  3.48 (2.64-4.59)   < .001  
Matched unrelated donor BM   
   G-CSF+ within 7 days after transplantation vs no G-CSF*  0.83 (0.67-1.03)   .09  
   Age   1.02 (1.01-1.03)   .02  
   KPS more than 80* vs less than 80%   1.40 (1.09-1.80)   .008  
   Recipient CMV status, negative vs positive*  0.69 (0.56-0.87)   .001  
   Disease stage at transplantation    
      Intermediate vs early*  1.46 (1.11-1.92)   .007  
      Advanced vs early*
 
2.64 (2.04-3.43)
 
< .001
 



Relative risk of death (95% CI)

P
HLA-identical sibling BM   
   G-CSF+ within 7 days after transplantation vs no G-CSF*  1.11 (0.90-1.36)   .35  
   Age   1.02 (1.01-1.03)   .004  
   KPS more than 80* vs less than 80%   1.34 (1.10-1.64)   .004  
   Disease stage at transplantation    
      Intermediate vs early*  1.99 (1.57-2.52)   < .001  
      Advanced vs early*  2.93 (2.35-3.65)   < .001  
HLA-identical sibling PBSCs   
   G-CSF+ within 7 days after transplantation vs no G-CSF*  1.07 (0.84-1.37)   .57  
   Age   1.02 (1.01-1.03)   .003  
   KPS more than 80* vs less than 80%   1.66 (1.29-2.13)   < .001  
   Disease stage at transplantation    
      Intermediate vs early*  1.60 (1.14-2.24)   .006  
      Advanced vs early*  3.48 (2.64-4.59)   < .001  
Matched unrelated donor BM   
   G-CSF+ within 7 days after transplantation vs no G-CSF*  0.83 (0.67-1.03)   .09  
   Age   1.02 (1.01-1.03)   .02  
   KPS more than 80* vs less than 80%   1.40 (1.09-1.80)   .008  
   Recipient CMV status, negative vs positive*  0.69 (0.56-0.87)   .001  
   Disease stage at transplantation    
      Intermediate vs early*  1.46 (1.11-1.92)   .007  
      Advanced vs early*
 
2.64 (2.04-3.43)
 
< .001
 

BM indicates bone marrow; G-CSF, granulocyte colony-stimulating factor; KPS, Karnofsky performance status; PBSC, peripheral blood stem cell; and CMV, cytomegalovirus.

*

Reference group

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