Table 1.

Surface expression of the ligands of DNAM-1 and NKG2D activating receptors and of HLA class I molecules in different MSC cell populations

DNAM-1 ligands
NKG2D ligands
Donor
Nectin-2 MRFI*
PVR MRFI
MICA/B and ULBPs†(MRFI)
HLA class I MRFI
1   8   24   ULBP3 (3)   69  
2   7   16   ULBP3 (3)   31  
3   3   8   ULBP3 (2)   10  
4   9   21   ULBP3 (2)   50  
5   7   35   ULBP1 (7), 2 (2), 3 (2), 4 (3)   47  
6   5   16   ULBP1 (2), 2 (3), 3 (4), 4 (3)   40  
7   12   33   ULBP2 (3), 3 (4)   61  
8   7   18   MICA (2), ULBP1 (2), 2 (2), 3 (2)   25  
9   4   6   MICA (2), ULBP2 (2), 3 (2)   8  
10   7   17   MICA (2), ULBP1 (2), 3 (2)   17  
11   6   10   ULBP1 (2), 3 (2)   20  
12   4   6   ULBP3 (2)   14  
13   8   15   MICA (2), ULBP3 (3)   30  
14   6   12   ULBP3 (2)   14  
15
 		 6
 		 10
 		 MICA (2), ULBP3 (3)
 		 38
 
DNAM-1 ligands
NKG2D ligands
Donor
Nectin-2 MRFI*
PVR MRFI
MICA/B and ULBPs†(MRFI)
HLA class I MRFI
1   8   24   ULBP3 (3)   69  
2   7   16   ULBP3 (3)   31  
3   3   8   ULBP3 (2)   10  
4   9   21   ULBP3 (2)   50  
5   7   35   ULBP1 (7), 2 (2), 3 (2), 4 (3)   47  
6   5   16   ULBP1 (2), 2 (3), 3 (4), 4 (3)   40  
7   12   33   ULBP2 (3), 3 (4)   61  
8   7   18   MICA (2), ULBP1 (2), 2 (2), 3 (2)   25  
9   4   6   MICA (2), ULBP2 (2), 3 (2)   8  
10   7   17   MICA (2), ULBP1 (2), 3 (2)   17  
11   6   10   ULBP1 (2), 3 (2)   20  
12   4   6   ULBP3 (2)   14  
13   8   15   MICA (2), ULBP3 (3)   30  
14   6   12   ULBP3 (2)   14  
15
 		 6
 		 10
 		 MICA (2), ULBP3 (3)
 		 38
 
*

Concerning MRFI, see “Materials and methods”

†

Only the expressed molecules among MICA and ULBP1-4 are indicated

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