VEGF receptors expressed at different frequencies in acute and chronic leukemia samples (primary leukemias and cell lines)
Type of leukemia . | FLT-1 positive, % . | KDR positive, % . | FLT-4 positive, % . |
|---|---|---|---|
| CML (n = 30) | 91 | 17.6 | 29.0 |
| ALL (n = 23) | 71 | 9.0 | 39.0 |
| AML (n = 30) | 78 | 28.0 | 2.8 |
Type of leukemia . | FLT-1 positive, % . | KDR positive, % . | FLT-4 positive, % . |
|---|---|---|---|
| CML (n = 30) | 91 | 17.6 | 29.0 |
| ALL (n = 23) | 71 | 9.0 | 39.0 |
| AML (n = 30) | 78 | 28.0 | 2.8 |
Leukemia blasts were obtained from BM samples of patients with different types of acute and chronic leukemias, and FLT-1, KDR, and FLT-4 positivity was determined by RT-PCR as described in “Materials and methods.”