Generation of B-lineage cells in IL-7–/– bone marrow cell cultures
. | scIL-7/HGFβ . | . | . | . | . | rIL-7 . | . | . | . | . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
. | CLP . | Pre-pro-B . | Pro-B . | Pre-B . | Total . | CLP . | Pre-pro-B . | Pro-B . | Pre-B . | Total . | ||||||||
| Input, day 1 | 2 | 5 | 4 | < 1 | 9 | 2 | 5 | 4 | < 1 | 9 | ||||||||
| Output, day 17 | 62 | 41 | 41 | < 1 | 144 | 0 | 2 | 205 | 32 | 239 | ||||||||
| Fold increase | 31 | 8 | 10 | 0 | 16 | 0 | 0 | 51 | > 32 | 27 | ||||||||
. | scIL-7/HGFβ . | . | . | . | . | rIL-7 . | . | . | . | . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
. | CLP . | Pre-pro-B . | Pro-B . | Pre-B . | Total . | CLP . | Pre-pro-B . | Pro-B . | Pre-B . | Total . | ||||||||
| Input, day 1 | 2 | 5 | 4 | < 1 | 9 | 2 | 5 | 4 | < 1 | 9 | ||||||||
| Output, day 17 | 62 | 41 | 41 | < 1 | 144 | 0 | 2 | 205 | 32 | 239 | ||||||||
| Fold increase | 31 | 8 | 10 | 0 | 16 | 0 | 0 | 51 | > 32 | 27 | ||||||||
Input and output values indicate number of cells (× 104) per well.