Role of GILZ in DEX-induced IL-10 production by MoDCs
. | DEX . | IL-10, pg/mL . |
|---|---|---|
| — | – | 176 ± 15 |
| — | + | 1068 ± 70 |
| siC | + | 1576 ± 76 |
| siGILZ | + | 487 ± 22 |
| pcDNA3 | – | 299 ± 35 |
| pGILZ | – | 1750 ± 85 |
. | DEX . | IL-10, pg/mL . |
|---|---|---|
| — | – | 176 ± 15 |
| — | + | 1068 ± 70 |
| siC | + | 1576 ± 76 |
| siGILZ | + | 487 ± 22 |
| pcDNA3 | – | 299 ± 35 |
| pGILZ | – | 1750 ± 85 |
IL-10 concentration (mean ± SEM) was measured in supernatants of immature MoDCs treated with DEX alone, with DEX and control, or GILZ siRNA, or in immature MoDCs nucleofected with a control (pcDNA3) or a GILZ-encoding (pGILZ) vector.