Table 2.

Combination therapy with nucleoside analogs and alkylators in Waldenström macroglobulinemia


Study

No. patients

Regimen

ORR, %

Response duration, mo
Tam et al14   9   Fludarabine/cyclophosphamide   88   13  
LeBlond et al20   49   Fludarabine/cyclophosphamide   78   27  
Weber et al12   37   Cladribine/cyclophosphamide   84   36  
Dimopoulos et al16 
 
11
 
Dexamethasone/cyclophosphamide/rituximab
 
55
 
NA
 

Study

No. patients

Regimen

ORR, %

Response duration, mo
Tam et al14   9   Fludarabine/cyclophosphamide   88   13  
LeBlond et al20   49   Fludarabine/cyclophosphamide   78   27  
Weber et al12   37   Cladribine/cyclophosphamide   84   36  
Dimopoulos et al16 
 
11
 
Dexamethasone/cyclophosphamide/rituximab
 
55
 
NA
 

NA indicates not applicable.

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