Hematopoietic indices of the Gata1S310A and Gata13SA mice
Genotype . | No. mice . | WBCs, × 106 cells/mL . | Eos, × 106 cells/mL . | RBCs, × 109 cells/mL . | HGB, g/dL . | HCT, % . | MCV, fL . | MCHC, g/dL . | Retics, % . | Platelets, × 106 cells/mL . | MPV, fL . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | 7 | 9.0 ± 1.1 | 2.2 ± 0.5 | 9.6 ± 0.3 | 15.5 ± 0.5 | 53.7 ± 1.9 | 56.2 ± 1.4 | 28.7 ± 0.8 | 2.6 ± 0.9 | 1268 ± 113 | 7.8 ± 0.2 |
| S310A KI | 8 | 7.9 ± 1.2 | 2.0 ± 0.3 | 9.0 ± 0.5 | 14.7 ± 0.9 | 51.6 ± 2.9 | 57.6 ± 1.1 | 28.4 ± 0.6 | 3.9 ± 0.8 | 1318 ± 208 | 7.9 ± 0.3 |
| WT | 10 | 7.6 ± 1.5 | 2.2 ± 1.1 | 9.6 ± 0.5 | 15.9 ± 1.1 | 53.6 ± 2.4 | 55.9 ± 1.8 | 29.6 ± 1.3 | 3.3 ± 1.2 | 1204 ± 103 | 7.4 ± 0.2 |
| 3SA KI | 8 | 7.0 ± 1.7 | 2.2 ± 1.0 | 9.5 ± 0.4 | 15.7 ± 0.4 | 53.9 ± 0.7 | 56.4 ± 2.3 | 29.3 ± 0.6 | 3.6 ± 0.8 | 1503 ± 133 | 7.8 ± 0.3 |
Genotype . | No. mice . | WBCs, × 106 cells/mL . | Eos, × 106 cells/mL . | RBCs, × 109 cells/mL . | HGB, g/dL . | HCT, % . | MCV, fL . | MCHC, g/dL . | Retics, % . | Platelets, × 106 cells/mL . | MPV, fL . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| WT | 7 | 9.0 ± 1.1 | 2.2 ± 0.5 | 9.6 ± 0.3 | 15.5 ± 0.5 | 53.7 ± 1.9 | 56.2 ± 1.4 | 28.7 ± 0.8 | 2.6 ± 0.9 | 1268 ± 113 | 7.8 ± 0.2 |
| S310A KI | 8 | 7.9 ± 1.2 | 2.0 ± 0.3 | 9.0 ± 0.5 | 14.7 ± 0.9 | 51.6 ± 2.9 | 57.6 ± 1.1 | 28.4 ± 0.6 | 3.9 ± 0.8 | 1318 ± 208 | 7.9 ± 0.3 |
| WT | 10 | 7.6 ± 1.5 | 2.2 ± 1.1 | 9.6 ± 0.5 | 15.9 ± 1.1 | 53.6 ± 2.4 | 55.9 ± 1.8 | 29.6 ± 1.3 | 3.3 ± 1.2 | 1204 ± 103 | 7.4 ± 0.2 |
| 3SA KI | 8 | 7.0 ± 1.7 | 2.2 ± 1.0 | 9.5 ± 0.4 | 15.7 ± 0.4 | 53.9 ± 0.7 | 56.4 ± 2.3 | 29.3 ± 0.6 | 3.6 ± 0.8 | 1503 ± 133 | 7.8 ± 0.3 |
All data are shown as mean plus or minus standard deviation.
WT indicates wild-type; WBC, white blood cell; Eos, eosinophils; RBC, red blood cell; HGB, hemoglobin; HCT, hematocrit; MCV, mean corpuscular volume; MCHC, mean corpuscular hgb concentration; Retics, reticulocytes; MPV, mean platelet volume.