Table 1.

Hematopoietic parameters of Hoxb4 mutants and control littermates



Cellularity

B-CFC

M-CFC

BM, × 106
Spleen, × 106
Thymus, × 106
BM, × 106
Spleen, × 106
BM, × 106
Spleen, × 106
Hoxb4−/−  29 ± 2.4   141 ± 74   97 ± 27   6.6 ± 2.4   0.4 ± 0.1   54 ± 2.4   3.8 ± 2.2  
Control
 
25 ± 5.3
 
152 ± 18
 
86 ± 13
 
4.4 ± 0.8
 
0.4 ± 0.3
 
41 ± 14
 
2.9 ± 0.4
 


Cellularity

B-CFC

M-CFC

BM, × 106
Spleen, × 106
Thymus, × 106
BM, × 106
Spleen, × 106
BM, × 106
Spleen, × 106
Hoxb4−/−  29 ± 2.4   141 ± 74   97 ± 27   6.6 ± 2.4   0.4 ± 0.1   54 ± 2.4   3.8 ± 2.2  
Control
 
25 ± 5.3
 
152 ± 18
 
86 ± 13
 
4.4 ± 0.8
 
0.4 ± 0.3
 
41 ± 14
 
2.9 ± 0.4
 

n = 3 mice for each group. Total cell numbers and numbers of B-cell and myeloid progenitors (B-cell and myeloid colony-forming cells, B-CFCs and M-CFCs, respectively) in BM, spleen, and thymus of Hoxb4−/− and control littermates.

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