Characteristics of CCG 2891 de novo patients
. | White . | . | . | Black . | . | . | Hispanic . | . | . | Asian . | . | . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
. | No. . | % . | P . | No. . | % . | P . | No. . | % . | P . | No. . | % . | P . | ||||||||
| Total | 558 | 70.5 | NA | 94 | 11.9 | NA | 114 | 14.4 | NA | 25 | 3.2 | NA | ||||||||
| Age, y | 7.8 | NA | .677 | 7.5 | NA | .756 | 7.9 | NA | .478 | 11.0 | NA | .436 | ||||||||
| Male | 282 | 50.5 | .617 | 42 | 44.7 | .348 | 70 | 61.4 | .044 | 11 | 44.0 | .663 | ||||||||
| WBC count | 22.7 | NA | .632 | 25.8 | NA | .844 | 20.4 | NA | .485 | 18.8 | NA | .613 | ||||||||
| CNS disease | 53 | 9.5 | .207 | 5 | 5.3 | .262 | 6 | 5.3 | .203 | 4 | 16.0 | .467 | ||||||||
| Induction timing | ||||||||||||||||||||
| INT | 351 | 62.9 | .316 | 50 | 53.2 | .094 | 71 | 62.3 | .985 | 16 | 64.0 | .920 | ||||||||
| STD | 196 | 35.1 | .191 | 44 | 46.8 | .040 | 41 | 36.0 | .949 | 9 | 36.0 | .901 | ||||||||
| STD/INT | 11 | 2.0 | .365 | 0 | 0.0 | .380 | 2 | 1.8 | 1.000 | 0 | 0.0 | >.999 | ||||||||
| Cytogenetics | ||||||||||||||||||||
| Normal | 80 | 25.7 | .902 | 11 | 20.8 | .548 | 11 | 28.2 | .889 | 3 | 60.0 | .116 | ||||||||
| t(8;21) | 35 | 11.3 | .235 | 7 | 13.2 | .858 | 8 | 20.5 | .117 | 1 | 20.0 | .456 | ||||||||
| Abn. 16 | 28 | 9.0 | .317 | 4 | 7.5 | >.999 | 1 | 2.6 | .227 | 0 | 0.0 | >.999 | ||||||||
| Abn. 11 | 64 | 20.6 | .009 | 4 | 7.5 | .022 | 4 | 10.3 | .186 | 0 | 0.0 | .587 | ||||||||
| t(6;9) | 3 | 1.0 | .341 | 1 | 1.9 | .469 | 1 | 2.6 | .378 | 0 | 0.0 | >.999 | ||||||||
| −7/7q- | 12 | 3.9 | .394 | 3 | 5.7 | .466 | 3 | 7.7 | .227 | 0 | 0.0 | >.999 | ||||||||
| −5/5q- | 4 | 1.3 | .364 | 2 | 3.8 | .212 | 1 | 2.6 | .448 | 0 | 0.0 | >.999 | ||||||||
| Trisomy 8 | 21 | 6.8 | .119 | 6 | 11.3 | .255 | 5 | 12.8 | .190 | 1 | 20.0 | .305 | ||||||||
| Trisomy 21 | 7 | 2.3 | .686 | 1 | 1.9 | >.999 | 0 | 0.0 | 1.000 | 0 | 0.0 | >.999 | ||||||||
| Other | 57 | 18.3 | .897 | 14 | 26.4 | .236 | 5 | 12.8 | .531 | 0 | 0.0 | .590 | ||||||||
| No data | 247 | NA | NA | 41 | NA | NA | 75 | NA | NA | 20 | NA | NA | ||||||||
. | White . | . | . | Black . | . | . | Hispanic . | . | . | Asian . | . | . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
. | No. . | % . | P . | No. . | % . | P . | No. . | % . | P . | No. . | % . | P . | ||||||||
| Total | 558 | 70.5 | NA | 94 | 11.9 | NA | 114 | 14.4 | NA | 25 | 3.2 | NA | ||||||||
| Age, y | 7.8 | NA | .677 | 7.5 | NA | .756 | 7.9 | NA | .478 | 11.0 | NA | .436 | ||||||||
| Male | 282 | 50.5 | .617 | 42 | 44.7 | .348 | 70 | 61.4 | .044 | 11 | 44.0 | .663 | ||||||||
| WBC count | 22.7 | NA | .632 | 25.8 | NA | .844 | 20.4 | NA | .485 | 18.8 | NA | .613 | ||||||||
| CNS disease | 53 | 9.5 | .207 | 5 | 5.3 | .262 | 6 | 5.3 | .203 | 4 | 16.0 | .467 | ||||||||
| Induction timing | ||||||||||||||||||||
| INT | 351 | 62.9 | .316 | 50 | 53.2 | .094 | 71 | 62.3 | .985 | 16 | 64.0 | .920 | ||||||||
| STD | 196 | 35.1 | .191 | 44 | 46.8 | .040 | 41 | 36.0 | .949 | 9 | 36.0 | .901 | ||||||||
| STD/INT | 11 | 2.0 | .365 | 0 | 0.0 | .380 | 2 | 1.8 | 1.000 | 0 | 0.0 | >.999 | ||||||||
| Cytogenetics | ||||||||||||||||||||
| Normal | 80 | 25.7 | .902 | 11 | 20.8 | .548 | 11 | 28.2 | .889 | 3 | 60.0 | .116 | ||||||||
| t(8;21) | 35 | 11.3 | .235 | 7 | 13.2 | .858 | 8 | 20.5 | .117 | 1 | 20.0 | .456 | ||||||||
| Abn. 16 | 28 | 9.0 | .317 | 4 | 7.5 | >.999 | 1 | 2.6 | .227 | 0 | 0.0 | >.999 | ||||||||
| Abn. 11 | 64 | 20.6 | .009 | 4 | 7.5 | .022 | 4 | 10.3 | .186 | 0 | 0.0 | .587 | ||||||||
| t(6;9) | 3 | 1.0 | .341 | 1 | 1.9 | .469 | 1 | 2.6 | .378 | 0 | 0.0 | >.999 | ||||||||
| −7/7q- | 12 | 3.9 | .394 | 3 | 5.7 | .466 | 3 | 7.7 | .227 | 0 | 0.0 | >.999 | ||||||||
| −5/5q- | 4 | 1.3 | .364 | 2 | 3.8 | .212 | 1 | 2.6 | .448 | 0 | 0.0 | >.999 | ||||||||
| Trisomy 8 | 21 | 6.8 | .119 | 6 | 11.3 | .255 | 5 | 12.8 | .190 | 1 | 20.0 | .305 | ||||||||
| Trisomy 21 | 7 | 2.3 | .686 | 1 | 1.9 | >.999 | 0 | 0.0 | 1.000 | 0 | 0.0 | >.999 | ||||||||
| Other | 57 | 18.3 | .897 | 14 | 26.4 | .236 | 5 | 12.8 | .531 | 0 | 0.0 | .590 | ||||||||
| No data | 247 | NA | NA | 41 | NA | NA | 75 | NA | NA | 20 | NA | NA | ||||||||
Median values reported for age and WBC count. For statistical analysis, white patients were compared with a combined ethnic group, and other ethnic groups were individually compared with white patients alone.
INT indicates intensive timing; STD, standard timing; STD/INT, combination intensive and standard timing; and NA, not applicable.