Characteristics of CCG 2961 de novo patients
. | White . | . | . | Black . | . | . | Hispanic . | . | . | Asian . | . | . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
. | No. . | % . | P . | No. . | % . | P . | No. . | % . | P . | No. . | % . | P . | ||||||||
| Total | 583 | 68.6 | — | 84 | 9.9 | — | 157 | 18.4 | — | 26 | 3.1 | — | ||||||||
| Age, y | 9.6 | — | .379 | 10.6 | — | .96 | 8.3 | — | .17 | 10.1 | — | .71 | ||||||||
| Male | 326 | 55.9 | < .001 | 39 | 46.4 | .13 | 62 | 39.5 | < .001 | 12 | 46.2 | .44 | ||||||||
| WBC count | 17.9 | — | .405 | 25.4 | — | .19 | 20.4 | .59 | 17.4 | .41 | ||||||||||
| CNS disease | 28 | 4.8 | .158 | 5 | 6.0 | .60 | 13 | 8.3 | .14 | 2 | 8.3 | .38 | ||||||||
| Cytogenetics | ||||||||||||||||||||
| Normal | 74 | 8.2 | .367 | 11 | 21.6 | .98 | 22 | 24.2 | .50 | 6 | 31.6 | .25 | ||||||||
| t(8;21) | 53 | 5.9 | .375 | 12 | 23.5 | .15 | 14 | 15.4 | .97 | 3 | 15.8 | .75 | ||||||||
| Abn. 16 | 31 | 3.4 | .712 | 3 | 5.9 | .78 | 12 | 13.2 | .24 | 1 | 5.3 | >.999 | ||||||||
| Abn. 11 | 89 | 9.9 | .389 | 12 | 23.5 | .97 | 17 | 18.7 | .31 | 4 | 21.1 | >.999 | ||||||||
| t(6;9) | 7 | 0.8 | >.999 | 2 | 3.9 | .30 | 1 | 1.1 | >.999 | 0 | 0.0 | >.999 | ||||||||
| −7/7q- | 13 | 1.4 | .852 | 1 | 2.0 | >.999 | 6 | 6.6 | .24 | 0 | 0.0 | >.999 | ||||||||
| −5/5q- | 5 | 0.6 | >.999 | 1 | 2.0 | .55 | 1 | 1.1 | >.999 | 0 | 0.0 | >.999 | ||||||||
| Trisomy 8 | 25 | 2.8 | .364 | 3 | 5.9 | >.999 | 3 | 3.3 | .31 | 1 | 5.3 | >.999 | ||||||||
| Trisomy 21 | 7 | 0.8 | .729 | 0 | 0.0 | >.999 | 2 | 2.2 | >.999 | 0 | 0.0 | >.999 | ||||||||
| Other | 61 | 6.8 | .568 | 6 | 11.8 | .24 | 13 | 14.3 | .69 | 4 | 21.1 | .54 | ||||||||
| No data | 218 | NA | NA | 33 | NA | NA | 66 | NA | NA | 7 | NA | NA | ||||||||
| FLT3/ITD | ||||||||||||||||||||
| Positive | 55 | 14.3 | .200 | 6 | 10.2 | .510 | 9 | 9.4 | .268 | 2 | 12.5 | .872 | ||||||||
| Negative | 329 | 85.7 | ND | 53 | 89.8 | ND | 87 | 90.6 | ND | 14 | 87.5 | NA | ||||||||
| No data | 199 | NA | NA | 25 | NA | NA | 61 | NA | NA | 10 | NA | NA | ||||||||
. | White . | . | . | Black . | . | . | Hispanic . | . | . | Asian . | . | . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
. | No. . | % . | P . | No. . | % . | P . | No. . | % . | P . | No. . | % . | P . | ||||||||
| Total | 583 | 68.6 | — | 84 | 9.9 | — | 157 | 18.4 | — | 26 | 3.1 | — | ||||||||
| Age, y | 9.6 | — | .379 | 10.6 | — | .96 | 8.3 | — | .17 | 10.1 | — | .71 | ||||||||
| Male | 326 | 55.9 | < .001 | 39 | 46.4 | .13 | 62 | 39.5 | < .001 | 12 | 46.2 | .44 | ||||||||
| WBC count | 17.9 | — | .405 | 25.4 | — | .19 | 20.4 | .59 | 17.4 | .41 | ||||||||||
| CNS disease | 28 | 4.8 | .158 | 5 | 6.0 | .60 | 13 | 8.3 | .14 | 2 | 8.3 | .38 | ||||||||
| Cytogenetics | ||||||||||||||||||||
| Normal | 74 | 8.2 | .367 | 11 | 21.6 | .98 | 22 | 24.2 | .50 | 6 | 31.6 | .25 | ||||||||
| t(8;21) | 53 | 5.9 | .375 | 12 | 23.5 | .15 | 14 | 15.4 | .97 | 3 | 15.8 | .75 | ||||||||
| Abn. 16 | 31 | 3.4 | .712 | 3 | 5.9 | .78 | 12 | 13.2 | .24 | 1 | 5.3 | >.999 | ||||||||
| Abn. 11 | 89 | 9.9 | .389 | 12 | 23.5 | .97 | 17 | 18.7 | .31 | 4 | 21.1 | >.999 | ||||||||
| t(6;9) | 7 | 0.8 | >.999 | 2 | 3.9 | .30 | 1 | 1.1 | >.999 | 0 | 0.0 | >.999 | ||||||||
| −7/7q- | 13 | 1.4 | .852 | 1 | 2.0 | >.999 | 6 | 6.6 | .24 | 0 | 0.0 | >.999 | ||||||||
| −5/5q- | 5 | 0.6 | >.999 | 1 | 2.0 | .55 | 1 | 1.1 | >.999 | 0 | 0.0 | >.999 | ||||||||
| Trisomy 8 | 25 | 2.8 | .364 | 3 | 5.9 | >.999 | 3 | 3.3 | .31 | 1 | 5.3 | >.999 | ||||||||
| Trisomy 21 | 7 | 0.8 | .729 | 0 | 0.0 | >.999 | 2 | 2.2 | >.999 | 0 | 0.0 | >.999 | ||||||||
| Other | 61 | 6.8 | .568 | 6 | 11.8 | .24 | 13 | 14.3 | .69 | 4 | 21.1 | .54 | ||||||||
| No data | 218 | NA | NA | 33 | NA | NA | 66 | NA | NA | 7 | NA | NA | ||||||||
| FLT3/ITD | ||||||||||||||||||||
| Positive | 55 | 14.3 | .200 | 6 | 10.2 | .510 | 9 | 9.4 | .268 | 2 | 12.5 | .872 | ||||||||
| Negative | 329 | 85.7 | ND | 53 | 89.8 | ND | 87 | 90.6 | ND | 14 | 87.5 | NA | ||||||||
| No data | 199 | NA | NA | 25 | NA | NA | 61 | NA | NA | 10 | NA | NA | ||||||||
For statistical analysis, white patients were compared with a combined group of other ethnic groups, and other ethnic groups were individually compared with white patients alone. Median values reported for age, WBC count, hemoglobin level, and platelet count.
NA indicates not applicable; ND, not done.