Nonhematologic side effects; n = 60
Side effect . | Grade 2 or lower (%) . | Grade 3 or higher (%) . |
|---|---|---|
| Diarrhea | 40 (67) | 3 (5) |
| Nausea | 40 (67) | 1 (2) |
| Headache | 40 (67) | — |
| Rash | 38 (63) | 11 (18)‡ |
| Hyperbilirubinemia | 35 (58) | 9 (15) |
| Flushing* | 35 (58) | 1 (2) |
| Vomiting | 31 (52) | — |
| Mucositis | 30 (50) | 2 (3) |
| ALT/AST elevation | 28 (47) | 10 (17) |
| Palmoplantar erythrodysesthesia† | 22 (37) | 2 (3) |
| Elevations of alkaline phosphatase | 10 (17) | 1 (2) |
| Extremity edema | 9 (15) | 1 (2) |
| Fatigue | 9 (15) | — |
| Pruritus | 7 (12) | — |
| Elevation of creatinine | 6 (10) | — |
| Ageusia | 6 (10) | — |
Side effect . | Grade 2 or lower (%) . | Grade 3 or higher (%) . |
|---|---|---|
| Diarrhea | 40 (67) | 3 (5) |
| Nausea | 40 (67) | 1 (2) |
| Headache | 40 (67) | — |
| Rash | 38 (63) | 11 (18)‡ |
| Hyperbilirubinemia | 35 (58) | 9 (15) |
| Flushing* | 35 (58) | 1 (2) |
| Vomiting | 31 (52) | — |
| Mucositis | 30 (50) | 2 (3) |
| ALT/AST elevation | 28 (47) | 10 (17) |
| Palmoplantar erythrodysesthesia† | 22 (37) | 2 (3) |
| Elevations of alkaline phosphatase | 10 (17) | 1 (2) |
| Extremity edema | 9 (15) | 1 (2) |
| Fatigue | 9 (15) | — |
| Pruritus | 7 (12) | — |
| Elevation of creatinine | 6 (10) | — |
| Ageusia | 6 (10) | — |