Table 3.

Overall survival (OS)







OS rate ± SE, %

Log-rank test*
Hazard ratio
95% CI
97.5% CI
12 mo
24 mo
36 mo
All patients  0.21   0.82   0.61-1.11   0.58-1.16     
Control, n = 160       70 ± 3.6   51 ± 4.0   44 ± 4.0  
HDC/IL-2, n = 160       78 ± 3.3   55 ± 4.0   48 ± 4.0  
Patients in CR1  0.16   0.78   0.56-1.09   0.53-1.15     
Control, n = 132       73 ± 3.9   53 ± 4.4   46 ± 4.4  
HDC/IL-2, n = 129       80 ± 3.5   61 ± 4.3   55 ± 4.4  
Patients in subsequent CR  > 0.5   1.00   0.52-1.93   0.47-2.13     
Control, n = 28       59 ± 9.5   41 ± 9.5   33 ± 9.1  
HDC/IL-2, n = 31
 

 

 

 

 
68 ± 8.4
 
32 ± 8.4
 
19 ± 7.1
 






OS rate ± SE, %

Log-rank test*
Hazard ratio
95% CI
97.5% CI
12 mo
24 mo
36 mo
All patients  0.21   0.82   0.61-1.11   0.58-1.16     
Control, n = 160       70 ± 3.6   51 ± 4.0   44 ± 4.0  
HDC/IL-2, n = 160       78 ± 3.3   55 ± 4.0   48 ± 4.0  
Patients in CR1  0.16   0.78   0.56-1.09   0.53-1.15     
Control, n = 132       73 ± 3.9   53 ± 4.4   46 ± 4.4  
HDC/IL-2, n = 129       80 ± 3.5   61 ± 4.3   55 ± 4.4  
Patients in subsequent CR  > 0.5   1.00   0.52-1.93   0.47-2.13     
Control, n = 28       59 ± 9.5   41 ± 9.5   33 ± 9.1  
HDC/IL-2, n = 31
 

 

 

 

 
68 ± 8.4
 
32 ± 8.4
 
19 ± 7.1
 
*

Statistical analysis using the log-rank test, stratified by country and, if applicable, CR stratum.

Confidence intervals for the hazard ratios of the treatment arms.

OS rates are Kaplan-Meier estimates at each time point.

or Create an Account

Close Modal
Close Modal